[HTML][HTML] Evolution of neuronal types and families

D Arendt, PY Bertucci, K Achim, JM Musser - Current opinion in …, 2019 - Elsevier
Highlights • Solving nervous system evolution requires cross-species comparison of neuronal
types. • Neuronal types are commonly defined by their specific structure and function. • We …

[HTML][HTML] The Nereid on the rise: Platynereis as a model system

…, G Andreatta, G Balavoine, PY Bertucci… - EvoDevo, 2021 - Springer
The Nereid Platynereis dumerilii (Audouin and Milne Edwards (Annales des Sciences Naturelles
1:195–269, 1833) is a marine annelid that belongs to the Nereididae, a family of errant …

[PDF][PDF] Whole-body integration of gene expression and single-cell morphology

…, KN Mutemi, B Titze, RM Templin, PY Bertucci… - Cell, 2021 - cell.com
Animal bodies are composed of cell types with unique expression programs that implement
their distinct locations, shapes, structures, and functions. Based on these properties, cell …

Whole-organism cellular gene-expression atlas reveals conserved cell types in the ventral nerve cord of Platynereis dumerilii

HM Vergara, PY Bertucci, P Hantz… - Proceedings of the …, 2017 - National Acad Sciences
The comparative study of cell types is a powerful approach toward deciphering animal
evolution. To avoid selection biases, however, comparisons ideally involve all cell types present …

Evolution of new cell types at the lateral neural border

J Stundl, PY Bertucci, A Lauri, D Arendt… - Current Topics in …, 2021 - Elsevier
During the course of evolution, animals have become increasingly complex by the addition of
novel cell types and regulatory mechanisms. A prime example is represented by the lateral …

Whole-body single-cell sequencing reveals transcriptional domains in the annelid larval body

…, N Eling, HM Vergara, PY Bertucci… - Molecular biology …, 2018 - academic.oup.com
Animal bodies comprise diverse arrays of cells. To characterize cellular identities across an
entire body, we have compared the transcriptomes of single cells randomly picked from …

The ancestral retinoic acid receptor was a low-affinity sensor triggering neuronal differentiation

…, ST Arold, E Kumar Nadendla, PY Bertucci… - Science …, 2018 - science.org
Retinoic acid (RA) is an important intercellular signaling molecule in vertebrate development,
with a well-established role in the regulation of hox genes during hindbrain patterning and …

Glucocorticoid-induced impairment of mammary gland involution is associated with STAT5 and STAT3 signaling modulation

PY Bertucci, A Quaglino, AG Pozzi, EC Kordon… - …, 2010 - academic.oup.com
The mammary epithelium undergoes cyclical periods of cellular proliferation, differentiation,
and regression. During lactation, the signal transducer and activator of transcription factor (…

Progesterone receptor induces bcl-x expression through intragenic binding sites favoring RNA polymerase II elongation

PY Bertucci, AS Nacht, M Allo… - Nucleic acids …, 2013 - academic.oup.com
Steroid receptors were classically described for regulating transcription by binding to target
gene promoters. However, genome-wide studies reveal that steroid receptors-binding sites …

Biological activity and ligand binding mode to the progesterone receptor of A-homo analogues of progesterone

LD Alvarez, MV Dansey, MA Martí, PY Bertucci… - Bioorganic & medicinal …, 2011 - Elsevier
The biological activity of two seven-membered A-ring (A-homo) analogues of progesterone
was evaluated by transactivation assays in Cos-1 cells and by determination of Bcl-x L …