Renal gluconeogenesis: an underestimated role of the kidney in systemic glucose metabolism

D Legouis, A Faivre, PE Cippā… - Nephrology dialysis …, 2022 - academic.oup.com
Glucose levels are tightly regulated at all times. Gluconeogenesis is the metabolic pathway
dedicated to glucose synthesis from non-hexose precursors. Gluconeogenesis is critical for …

Cytomegalovirus post kidney transplantation: prophylaxis versus pre‐emptive therapy?

T Fehr, PE Cippā, NJ Mueller - Transplant International, 2015 - Wiley Online Library
Cytomegalovirus is the most important pathogen causing opportunistic infections in kidney
allograft recipients. The occurrence of CMV disease is associated with higher morbidity, …

[HTML][HTML] Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift

…, H Chu, A Gori, A Riva, O Giannini, A Ceschi, P Ferrari… - Nature, 2022 - nature.com
… Statistical significance is set as P < 0.05 and P values are indicated with asterisks (*P =
0.033; **P = 0.002; ***P < 0.001), using a paired two-sided t-test (Wilcoxon rank test). …

Broad betacoronavirus neutralization by a stem helix–specific human antibody

…, R Marzi, E Vetti, A Cassotta, A Ceschi, P Ferrari… - Science, 2021 - science.org
The spillovers of betacoronaviruses in humans and the emergence of severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) variants highlight the need for broad coronavirus …

[HTML][HTML] Neutralization, effector function and immune imprinting of Omicron variants

…, B Whitener, O Giannini, P Cippā, A Ceschi, P Ferrari… - Nature, 2023 - nature.com
… R 2 and P values are derived from two-tailed Pearson correlation. f, Body weight loss (left)
and lung viral RNA load (right) on day 6 after infection of K18-hACE2 mice receiving S309, …

Single-nuclear transcriptomics reveals diversity of proximal tubule cell states in a dynamic response to acute kidney injury

LMS Gerhardt, J Liu, K Koppitch… - Proceedings of the …, 2021 - National Acad Sciences
Acute kidney injury (AKI), commonly caused by ischemia, sepsis, or nephrotoxic insult, is
associated with increased mortality and a heightened risk of chronic kidney disease (CKD). AKI …

[HTML][HTML] Molecular characterization of the transition from acute to chronic kidney injury following ischemia/reperfusion

J Liu, S Kumar, E Dolzhenko, GF Alvarado, J Guo… - JCI insight, 2017 - ncbi.nlm.nih.gov
… (C) Histogram of –log10 of P values of DAVID gene ontology for biological processes of …
seq data at the gene level by quantifying fragments per kilobase of transcript per million mapped …

Altered proximal tubular cell glucose metabolism during acute kidney injury is associated with mortality

…, T Verissimo, K Gariani, C Verney, P Galichon… - Nature …, 2020 - nature.com
P values were calculated from a two-tailed Wald test. g, Stacked bar plots showing metabolism
pattern over time in ICU patients with AKI and receiving (n = 347 patients) or not (n = 694 …

Proximal tubule responses to injury: interrogation by single-cell transcriptomics

PE Cippā, AP McMahon - Current Opinion in Nephrology and …, 2023 - journals.lww.com
We provide an update on single-cell technologies and we summarize the recent discoveries
on the cellular response to injury in proximal tubule cells from the early response in AKI, to …

Risk stratification for rejection and infection after kidney transplantation

PE Cippā, M Schiesser, H Ekberg… - Clinical Journal of the …, 2015 - journals.lww.com
… These tests and all other statistical tests were two sided, and P values <0.05 were considered
to … of composite end points (P<0.001), rejection episodes (P<0.01), and infection episodes (…