A substantial number of clinical trials using antiangiogenic therapies are ongoing worldwide.
How to achieve the maximum benefit from these therapies and how to monitor patient …

The ‘gene-centric’ approach has produced a wealth of information about the origins and
progression of cancer, and investigators seek a full compilation of altered gene expressions for …

The effects of the angiogenic inhibitors endostatin, angiostatin, and TNP-470 on tumor growth
dynamics are experimentally and theoretically investigated. On the basis of the data, we …

… factors” were more often found to be underexpressed after endostatin treatment (p … In
contrast, “stress” genes were more often found to be upregulated (p 0.04). Transcripts encoding …

… The statistical representation is then formula (7) with β instead of β j , together with Two
coefficients (the vector μ of length p and the p×p matrix ω) represent the total population, instead …

… Results: Her-2-neu protein expression was statistically significantly higher in TAA tumors
than in UNT tumors with the use of two different scoring methods (P = .008 and P = .002). The …

Several drugs approved for a variety of indications have been shown to exhibit antiangiogenic
effects. Our study focuses on the PPARγ ligand rosiglitazone, a compound widely used in …

Models of tumor growth and treatment based on one or two ordinary differential equations are
heavily used in practice because they are simple but can often still capture the essence of …

A shift of the angiogenic balance to the proangiogenic state, termed the “angiogenic switch,”
is a hallmark of cancer progression. Here we devise a strategy for identifying genetic …

One of the fundamental tools in radiation biology is a formalism describing time-dose
relationships. For example, there is a need for reliable predictions of radiotherapeutic isoeffect …