Chemokines are a superfamily of small proteins that bind to G protein-coupled receptors on
target cells and were originally discovered as mediators of directional migration of immune …

Members of the Toll-like receptor (TLR) family play key roles in both innate and adaptive
immune responses. TLR proteins enable host to recognize a large number of pathogen-…

… Once activated, this complex produces phosphatidylinositol-3-phosphate (PtdIns(3)P),
which recruits effector molecules such as double FYVE-containing protein 1 (DFCP1) and WD-…

… The cells were washed with PBS (0.2% Nonidet P-40) for 5 min, and the slides were
mounted with … Values of p equal to or less than 0.05 were considered statistically significant. …

The human G-protein-coupled formyl peptide receptor-like 1 (FPRL1) and its mouse
homologue mFPR2 mediate the chemotactic activity of a variety of polypeptides associated with …

The activation of innate immune response is initiated by engagement of pattern-recognition
receptors (PPRs), such as Toll-like receptors (TLRs). These receptors are expressed in …

… and transferred to Immobilon P membranes. The blots were then incubated with primary
antibodies against STAT3 phosphorylated at Tyr-705 (p-Tyr705) or at Ser-727 (p-Ser727), …

… P-selectin receptor P-selectin glycoprotein ligand-1 (6). Human CaG has been shown to
promote specific Ab responses when injected in mice (7). In addition, CaG has been implicated …

… Cells were lysed and p38, p-p38, ERK1/2, p-ERK1/2 and b-actin levels were analysed by
Western immunoblotting. Quantification by densitometry of p-p38 (C) or p-ERK1/2 (D) from B …

Alzheimer disease (AD) is the most common neurodegenerative disease, affecting approx 4
million people in the United States in the year 2000 alone. Amyloid β (Aβ) deposition, …