User profiles for P. Khoueiry

Pierre Khoueiry

Boehringer-Ingelheim
Verified email at boehringer-ingelheim.com
Cited by 881

[PDF][PDF] Shadow enhancers are pervasive features of developmental regulatory networks

E Cannavò, P Khoueiry, DA Garfield, P Geeleher… - Current Biology, 2016 - cell.com
… However, they are not more likely to exhibit identical activity than expected by chance (p =
… overlapping spatial expression (p = 2.6 3 10 À61 ) and identical expression (p = 0.001) than …

[HTML][HTML] Rules governing selective protein carbonylation

E Maisonneuve, A Ducret, P Khoueiry, S Lignon… - PloS one, 2009 - journals.plos.org
… As the percentage of solvent accessible R, K, P, and T sites within BSA is close to 80%, our
results suggest no over-representation of solvent accessible CS within carbonylatable sites. …

The ANISEED database: digital representation, formalization, and elucidation of a chordate developmental program

…, F Daian, D Sobral, F Robin, P Khoueiry… - Genome …, 2010 - genome.cshlp.org
Developmental biology aims to understand how the dynamics of embryonic shapes and
organ functions are encoded in linear DNA molecules. Thanks to recent progress in genomics …

[HTML][HTML] Ten simple rules for organizing an unconference

…, L Rubinat, DP Devos, PH Khoueiry… - PLoS computational …, 2015 - journals.plos.org
An academic conference is a traditional platform for researchers and professionals to
network and learn about recent developments and trends in a particular academic field [1–4]. …

Uncoupling evolutionary changes in DNA sequence, transcription factor occupancy and enhancer activity

P Khoueiry, C Girardot, L Ciglar, PC Peng… - Elife, 2017 - elifesciences.org
… Overall p-value corresponds to a two-sided proportions test, p-values within categories
correspond to Fisher exact test. (e) CRMs with strong or intermediate conservation in their TF …

[HTML][HTML] Clinically relevant bleeding in cancer patients treated for venous thromboembolism from the CATCH study

…, J Miscuks, D Abigerges, F Farhat, P Khoueiry… - Journal of Thrombosis …, 2018 - Elsevier
… For a risk factor found to be significantly associated with an increased risk of CRB according
to Fisher's exact test (P< 0.05), a competing risk regression analysis of time to first CRB …

[PDF][PDF] A cis-regulatory signature in ascidians and flies, independent of transcription factor binding sites

P Khoueiry, U Rothbächer, Y Ohtsuka, F Daian… - Current Biology, 2010 - cell.com
Background Transcription initiation is controlled by cis-regulatory modules. Although these
modules are usually made of clusters of short transcription factor binding sites, a small …

[HTML][HTML] Discovery of new fusion transcripts in a cohort of pediatric solid cancers at relapse and relevance for personalized medicine

…, W Rondof, G Robert-Siegwald, P Khoueiry… - Molecular Therapy, 2019 - cell.com
We hypothetized that pediatric cancers would more likely harbor fusion transcripts. To dissect
the complexity of the fusions landscape in recurrent solid pediatric cancers, we conducted …

[HTML][HTML] BRD4 bimodal binding at promoters and drug-induced displacement at Pol II pause sites associates with I-BET sensitivity

P Khoueiry, A Ward Gahlawat, M Petretich… - Epigenetics & …, 2019 - Springer
Background Deregulated transcription is a major driver of diseases such as cancer.
Bromodomain and extra-terminal (BET) proteins (BRD2, BRD3, BRD4 and BRDT) are chromatin …

[HTML][HTML] Uncovering a novel role of focal adhesion and interferon-gamma in cellular rejection of kidney allografts at single cell resolution

…, P Cravedi, A Greka, P Khoueiry… - Frontiers in …, 2023 - frontiersin.org
Background Kidney transplant recipients are currently treated with nonspecific
immunosuppressants that cause severe systemic side effects. Current immunosuppressants were …