User profiles for P. Lemey

Philippe Lemey

Full Professor, KU Leuven
Verified email at kuleuven.be
Cited by 41333

Respiratory syncytial virus prevention within reach: the vaccine and monoclonal antibody landscape

…, L Kragten-Tabatabaie, P Lemey… - The Lancet Infectious …, 2023 - thelancet.com
Respiratory syncytial virus is the second most common cause of infant mortality and a major
cause of morbidity and mortality in older adults (aged >60 years). Efforts to develop a …

[HTML][HTML] Tracking virus outbreaks in the twenty-first century

ND Grubaugh, JT Ladner, P Lemey, OG Pybus… - Nature …, 2019 - nature.com
Emerging viruses have the potential to impose substantial mortality, morbidity and economic
burdens on human populations. Tracking the spread of infectious diseases to assist in their …

RDP3: a flexible and fast computer program for analyzing recombination

DP Martin, P Lemey, M Lott, V Moulton, D Posada… - …, 2010 - academic.oup.com
RDP3 is a new version of the RDP program for characterizing recombination events in DNA-sequence
alignments. Among other novelties, this version includes four new recombination …

Analysing recombination in nucleotide sequences

DP Martin, P Lemey, D Posada - Molecular Ecology Resources, 2011 - Wiley Online Library
Throughout the living world, genetic recombination and nucleotide substitution are the
primary processes that create the genetic variation upon which natural selection acts. Just as …

[PDF][PDF] Bayesian phylogenetic and phylodynamic data integration using BEAST 1.10

MA Suchard, P Lemey, G Baele, DL Ayres… - Virus …, 2018 - academic.oup.com
The Bayesian Evolutionary Analysis by Sampling Trees (BEAST) software package has
become a primary tool for Bayesian phylogenetic and phylodynamic inference from genetic …

Evolution and epidemic spread of SARS-CoV-2 in Brazil

…, ATR Vasconcelos, S Bhatt, P Lemey… - Science, 2020 - science.org
Brazil currently has one of the fastest-growing severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) epidemics in the world. Because of limited available data, assessments …

[HTML][HTML] Bayesian phylogeography finds its roots

P Lemey, A Rambaut, AJ Drummond… - PLoS computational …, 2009 - journals.plos.org
As a key factor in endemic and epidemic dynamics, the geographical distribution of viruses
has been frequently interpreted in the light of their genetic histories. Unfortunately, inference …

The Huanan Seafood Wholesale Market in Wuhan was the early epicenter of the COVID-19 pandemic

…, MPG Koopmans, MA Suchard, JO Wertheim, P Lemey… - Science, 2022 - science.org
… We found evidence (P < 0.05) of a region in the southwest area of the market where live
mammals were for sale (Fig. 4B). Although environmental sampling of the market was …

Improving the accuracy of demographic and molecular clock model comparison while accommodating phylogenetic uncertainty

G Baele, P Lemey, T Bedford, A Rambaut… - Molecular biology …, 2012 - academic.oup.com
… In order to evaluate model fit and calculate BFs, the normalization constant or marginal
likelihood p(Y|M), which measures the average fit of a model to the data, is of primary importance. …

[HTML][HTML] Evolutionary origins of the SARS-CoV-2 sarbecovirus lineage responsible for the COVID-19 pandemic

MF Boni, P Lemey, X Jiang, TTY Lam, BW Perry… - Nature …, 2020 - nature.com
There are outstanding evolutionary questions on the recent emergence of human coronavirus
SARS-CoV-2 including the role of reservoir species, the role of recombination and its time …