User profiles for P. McGarvey

Peter McGarvey

Professor, Biochemistry at Georgetown Medical Center
Verified email at georgetown.edu
Cited by 51109

[HTML][HTML] A crowdsourcing open platform for literature curation in UniProt

…, H Huang, W Huang, Y Chen, PB McGarvey… - PLoS …, 2021 - journals.plos.org
The UniProt knowledgebase is a public database for protein sequence and function, covering
the tree of life and over 220 million protein entries. Now, the whole community can use a …

UniRef clusters: a comprehensive and scalable alternative for improving sequence similarity searches

BE Suzek, Y Wang, H Huang, PB McGarvey… - …, 2015 - academic.oup.com
… In defining the levels of consistency, we used the GO term specificity (P) metric computed …
The P = 1.0 means a GO term has no descendants (the most specific) and P = 0.0 means the …

UniRef: comprehensive and non-redundant UniProt reference clusters

BE Suzek, H Huang, P McGarvey, R Mazumder… - …, 2007 - academic.oup.com
Motivation: Redundant protein sequences in biological databases hinder sequence similarity
searches and make interpretation of search results difficult. Clustering of protein sequence …

[HTML][HTML] Integrated proteogenomic characterization of human high-grade serous ovarian cancer

…, NJ Edwards, PB McGarvey, S Madhavan, P Wang… - Cell, 2016 - cell.com
To provide a detailed analysis of the molecular components and underlying mechanisms
associated with ovarian cancer, we performed a comprehensive mass-spectrometry-based …

[PDF][PDF] Proteogenomic characterization reveals therapeutic vulnerabilities in lung adenocarcinoma

…, P Grady, PB McGarvey, P Mieczkowski, P Hariharan… - Cell, 2020 - cell.com
To explore the biology of lung adenocarcinoma (LUAD) and identify new therapeutic
opportunities, we performed comprehensive proteogenomic characterization of 110 tumors and …

[PDF][PDF] Proteogenomic characterization of pancreatic ductal adenocarcinoma

…, R Matteotti, N Maunganidze, PB McGarvey, P Minoo… - Cell, 2021 - cell.com
… (E) Cox regression signed p value for phosphosite and N-linked glycosylation site
abundance association with survival compared to the protein association to survival. …

[PDF][PDF] Proteogenomic analysis of human colon cancer reveals new therapeutic opportunities

…, N Vatanian, PA Rudnick, PB McGarvey, P Mertins… - Cell, 2019 - cell.com
We performed the first proteogenomic study on a prospectively collected colon cancer cohort.
Comparative proteomic and phosphoproteomic analysis of paired tumor and normal …

[HTML][HTML] Infrastructure for the life sciences: design and implementation of the UniProt website

…, N Redaschi, BE Suzek, MJ Martin, P McGarvey… - BMC …, 2009 - Springer
Background The UniProt consortium was formed in 2002 by groups from the Swiss Institute
of Bioinformatics (SIB), the European Bioinformatics Institute (EBI) and the Protein …

[PDF][PDF] A proteogenomic portrait of lung squamous cell carcinoma

…, O Fadare, P Grady, PB McGarvey, P Hariharan… - Cell, 2021 - cell.com
Lung squamous cell carcinoma (LSCC) remains a leading cause of cancer death with few
therapeutic options. We characterized the proteogenomic landscape of LSCC, providing a …

Expression of the rabies virus glycoprotein in transgenic tomatoes

PB McGarvey, J Hammond, MM Dienelt, DC Hooper… - Bio/technology, 1995 - nature.com
… The neomycin phosphotransferase ll (NPTll) gene provides kanamycin resistance in plants
and is under the control of the nopaline synthase promoter (NOS-P). Arrows indicate the …