[HTML][HTML] Amphioxus functional genomics and the origins of vertebrate gene regulation
Vertebrates have greatly elaborated the basic chordate body plan and evolved highly
distinctive genomes that have been sculpted by two whole-genome duplications. Here we …
distinctive genomes that have been sculpted by two whole-genome duplications. Here we …
[HTML][HTML] Genomic adaptations to aquatic and aerial life in mayflies and the origin of insect wings
The evolution of winged insects revolutionized terrestrial ecosystems and led to the largest
animal radiation on Earth. However, we still have an incomplete picture of the genomic …
animal radiation on Earth. However, we still have an incomplete picture of the genomic …
[HTML][HTML] Dynamic changes in the epigenomic landscape regulate human organogenesis and link to developmental disorders
How the genome activates or silences transcriptional programmes governs organ formation.
Little is known in human embryos undermining our ability to benchmark the fidelity of stem …
Little is known in human embryos undermining our ability to benchmark the fidelity of stem …
Ancient genomic regulatory blocks are a source for regulatory gene deserts in vertebrates after whole-genome duplications
…, EM Kita, RD Acemel, PN Firbas… - Molecular Biology …, 2020 - academic.oup.com
We investigated how the two rounds of whole-genome duplication that occurred at the base
of the vertebrate lineage have impacted ancient microsyntenic associations involving …
of the vertebrate lineage have impacted ancient microsyntenic associations involving …
[HTML][HTML] Multidimensional chromatin profiling of zebrafish pancreas to uncover and investigate disease-relevant enhancers
…, M Galhardo, D Ribeiro, RD Acemel, PN Firbas… - Nature …, 2022 - nature.com
The pancreas is a central organ for human diseases. Most alleles uncovered by genome-wide
association studies of pancreatic dysfunction traits overlap with non-coding sequences of …
association studies of pancreatic dysfunction traits overlap with non-coding sequences of …
Cis-regulatory similarities in the zebrafish and human pancreas uncover potential disease-related enhancers
…, D Ribeiro, R Dominguez-Acemel, PN Firbas… - bioRxiv, 2020 - biorxiv.org
Introductory paragraph The pancreas is a central organ for human diseases that have a
dramatic societal burden, such as pancreatic cancer and diabetes 1 , 2 . Non-coding cis-…
dramatic societal burden, such as pancreatic cancer and diabetes 1 , 2 . Non-coding cis-…
Genomic adaptations to aquatic and aerial life in mayflies and the origin of insect wings
…, A de Mendoza, F Marlétaz, PN Firbas… - … , 2020, vol. 11, num …, 2020 - diposit.ub.edu
The evolution of winged insects revolutionized terrestrial ecosystems and led to the largest
animal radiation on Earth. However, we still have an incomplete picture of the genomic …
animal radiation on Earth. However, we still have an incomplete picture of the genomic …
The epigenomic landscape regulating organogenesis in human embryos linked to developmental disorders
How the genome activates or silences transcriptional programmes governs organ formation.
Little is known in human embryos undermining our ability to benchmark the fidelity of in vitro …
Little is known in human embryos undermining our ability to benchmark the fidelity of in vitro …
Ancient genomic regulatory blocks are a major source for gene deserts in vertebrates after whole genome duplications
M Touceda-Suárez, EM Kita, RD Acemel, PN Firbas… - bioRxiv, 2019 - biorxiv.org
We investigated how the two rounds of whole genome duplication that occurred at the base
of the vertebrate lineage have impacted ancient microsyntenic associations involving …
of the vertebrate lineage have impacted ancient microsyntenic associations involving …
Application of 3-D crustal and upper mantle velocity model of North America for location of regional seismic events
V Ryaboy, DR Baumgardt, P Firbas… - … Nuclear-Test-Ban Treaty …, 2001 - Springer
… Pn travel times recorded from the calibration events were collected and carefully evaluated.
Data from all available seismic stations were used in this study to derive maps of Pn travel-…
Data from all available seismic stations were used in this study to derive maps of Pn travel-…