User profiles for P. Oatley

Peter Oatley

University of Central Lancashire
Verified email at uclan.ac.uk
Cited by 235

Two-way communication between SecY and SecA suggests a Brownian ratchet mechanism for protein translocation

WJ Allen, RA Corey, P Oatley, RB Sessions… - elife, 2016 - elifesciences.org
… Allen, Corey, Oatley et al. have now used a combination of experimental and computational
methods to look at how the different parts of Sec move around as it uses ATP. The reasoning …

Dynamic action of the Sec machinery during initiation, protein translocation and termination

T Fessl, D Watkins, P Oatley, WJ Allen, RA Corey… - Elife, 2018 - elifesciences.org
… In our experiments, this likelihood remained high (p>0.9) for up to 80 ms, allowing us to
extend the observation window. Therefore, the experimental setup provides a large window in …

[HTML][HTML] Spatial organization of Clostridium difficile S-layer biogenesis

P Oatley, JA Kirk, S Ma, S Jones, RP Fagan - Scientific Reports, 2020 - nature.com
Surface layers (S-layers) are protective protein coats which form around all archaea and most
bacterial cells. Clostridium difficile is a Gram-positive bacterium with an S-layer covering …

[HTML][HTML] A cortex-specific penicillin-binding protein contributes to heat resistance in Clostridioides difficile spores

YAJ Alabdali, P Oatley, JA Kirk, RP Fagan - Anaerobe, 2021 - Elsevier
Background Sporulation is a complex cell differentiation programme shared by many members
of the Firmicutes, the end result of which is a highly resistant, metabolically inert spore …

Atomic force microscopy imaging reveals the domain structure of polycystin-1

P Oatley, AP Stewart, R Sandford, JM Edwardson - Biochemistry, 2012 - ACS Publications
Mutation of polycystin-1 (PC1) is the major cause of autosomal dominant polycystic kidney
disease. PC1 has a predicted molecular mass of ∼460 kDa comprising a long multidomain …

A comparative analysis of movements of southern African waterfowl (Anatidae), based on ringing recoveries

RP Oatley, TO* & and Prys-Jones - South African Journal of Wildlife …, 1986 - journals.co.za
… 377) that the yellowbilled duck is highly migratory is unsupported for southern African birds,
even allowing for the broad and vague definition of the term migration that he uses (p. ix), …

Polycystin-2 induces a conformational change in polycystin-1

P Oatley, MMU Talukder, AP Stewart, R Sandford… - Biochemistry, 2013 - ACS Publications
Autosomal dominant polycystic kidney disease (ADPKD) is caused by mutations in the
genes encoding either polycystin-1 (PC1) or polycystin-2 (PC2). PC2 acts as a nonselective …

2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin (TCDD) as a potent and persistent thyroxine agonist: a mechanistic model for toxicity based on molecular reactivity.

…, J Fawkes, S Jordan, K Chae, S Oatley… - Environmental …, 1985 - ehp.niehs.nih.gov
TCDD and thyroxine have common molecular reactivity properties which enable them to
present a planar face and lateral halogens in interactions with proteins. These molecular …

Molecular interactions of toxic chlorinated dibenzo-p-dioxins and dibenzofurans with thyroxine binding prealbumin

JD McKinney, K Chae, SJ Oatley… - Journal of medicinal …, 1985 - ACS Publications
The interactions of 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin and related compounds with
prealbumin, a model for the nuclear thyroid hormone receptor, have been studied with use of …

Positively charged nanofiltration membranes: review of current fabrication methods and introduction of a novel approach

S Cheng, DL Oatley, PM Williams, CJ Wright - Advances in Colloid and …, 2011 - Elsevier
… Rejection of solute was calculated using the following equation,(1) R obs = 1 − C p C b where
C p … Therefore, real rejection is defined as,(2) R real = 1 − C p C w where C w is the solute …