User profiles for P. Obeid

Pierre J Obeid

University of Balamand
Verified email at balamand.edu.lb
Cited by 963

Effects of smoking on periodontal health: a review

P Obeid, P Bercy - Advances in therapy, 2000 - Springer
Cigarette smoking is a risk factor for several diseases, and recent evidence strongly suggests
an adverse effect on periodontal health. Nevertheless, the nature of the relationship …

Microfabricated device for DNA and RNA amplification by continuous-flow polymerase chain reaction and reverse transcription-polymerase chain reaction with cycle …

PJ Obeid, TK Christopoulos, HJ Crabtree… - Analytical …, 2003 - ACS Publications
We have developed a high-throughput microfabricated, reusable glass chip for the
functional integration of reverse transcription (RT) and polymerase chain reaction (PCR) in a …

Immune checkpoint inhibition in GBM primed with radiation by engineered extracellular vesicles

T Tian, R Liang, G Erel-Akbaba, L Saad, PJ Obeid… - Acs Nano, 2022 - ACS Publications
The lack of safe and effective delivery across the blood-brain barrier and the profound immune
suppressive microenvironment are two main hurdles to glioblastoma (GBM) therapies. …

Radiation-induced targeted nanoparticle-based gene delivery for brain tumor therapy

…, LA Carvalho, T Tian, M Zinter, H Akbaba, PJ Obeid… - ACS …, 2019 - ACS Publications
Targeted therapy against the programmed cell death ligand-1 (PD-L1) blockade holds
considerable promise for the treatment of different tumor types; however, little effect has been …

[HTML][HTML] High-content monitoring of drug effects in a 3D spheroid model

F Mittler, P Obeïd, AV Rulina, V Haguet, X Gidrol… - Frontiers in …, 2017 - frontiersin.org
A recent decline in the discovery of novel medications challenges the widespread use of 2D
monolayer cell assays in the drug discovery process. As a result, the need for more …

Comparative clinical responses related to the use of various periodontal instrumentation

PR Obeid, W D'hoore, P Bercy - Journal of clinical …, 2004 - Wiley Online Library
Aim: The aim of this study was to evaluate in vivo the effectiveness of scaling and root
planing of a power‐driven mechanism compared with hand instruments and ultrasonic insert …

Continuous-flow DNA and RNA amplification chip combined with laser-induced fluorescence detection

PJ Obeid, TK Christopoulos - Analytica Chimica Acta, 2003 - Elsevier
… The linear range obtained by using the in-house constructed LIF system, was comparable
to that obtained using the Beckman P/ACE System 2100 for capillary electrophoresis …

The application of 3D micropatterning of agarose substrate for cell culture and in situ comet assays

E Mercey, P Obeïd, D Glaise, ML Calvo-Muñoz… - Biomaterials, 2010 - Elsevier
We report the fabrication of a 3D micropatterned agarose substrate that enables the culture
of single or multiple cells. Patterning was performed on dried agarose using deep UV …

Continuous microcarrier-based cell culture in a benchtop microfluidic bioreactor

F Abeille, F Mittler, P Obeïd, M Huet, F Kermarrec… - Lab on a Chip, 2014 - pubs.rsc.org
Microfluidic bioreactors are expected to impact cell therapy and biopharmaceutical production
due to their ability to control cellular microenvironments. This work presents a novel …

[HTML][HTML] A new ultradian rhythm in mammalian cell dry mass observed by holography

L Ghenim, C Allier, P Obeid, L Hervé, JY Fortin… - Scientific Reports, 2021 - nature.com
We have discovered a new 4 h ultradian rhythm that occurs during the interphase of the cell
cycle in a wide range of individual mammalian cells, including both primary and transformed …