An attractive path forward in proteomics is to experimentally annotate the human protein
complement of the genome in a genecentric manner. Using antibodies, it might be possible to …

… 13 organ systems, as described in (P), and the fraction of all transcripts (FPKM) encoded by
these elevated genes for each of these organ systems. (P) An analysis of major GO terms for …

… for five of the cancer types, based on the optimal stratification P value calculated for each
gene and cancer. In each case, a significant separation (P < 0.001) of the survival rate could be …

INTRODUCTION A complete view of human biology can only be achieved by studying the
molecular components of its smallest functional unit, the cell. Cells are internally organized …

Global classification of the human proteins with regards to spatial expression patterns across
organs and tissues is important for studies of human biology and disease. Here, we used a …

Advances in molecular profiling have opened up the possibility to map the expression of
genes in cells, tissues, and organs in the human body. Here, we combined single-cell …

Antibody-based proteomics provides a powerful approach for the functional study of the
human proteome involving the systematic generation of protein-specific affinity reagents. We …

NATURE BIoTECHNoloGy volume 28 number 12 DeCember 2010 1249 the resulting
annotated protein expression. The annotated protein expression in the various cell types are …

INTRODUCTION The brain is the most complex organ of the mammalian body, boasting a
diverse physiology combined with intricate cellular organization. In an effort to expand our …

INTRODUCTION Blood is the predominant source for molecular analyses in humans, both
in clinical and research settings, and is the target for many therapeutic strategies, …