User profiles for P. Pouchin

Pierre Pouchin

INSERM
Verified email at inserm.fr
Cited by 599

[PDF][PDF] Primitive endoderm differentiates via a three-step mechanism involving Nanog and RTK signaling

…, F Gerbe, S Bessonnard, C Belville, P Pouchin… - Developmental cell, 2011 - cell.com
… directly on p-Erk, whereas at later stages an absence of Nanog appears to be sufficient.
Ultimately, absence of both Nanog and p-Erk, in the presence of Gata6, results in cell death. …

[HTML][HTML] NANOG initiates epiblast fate through the coordination of pluripotency genes expression

…, D Meistermann, LV Estrella, P Pouchin… - Nature …, 2022 - nature.com
… The mean is represented by a square, the median by the central line; *p < 0.05, **p < 0.01
(Two-sided Wilcoxon test relative to the WT sample, see Supplementary data 15 for exact p

[HTML][HTML] A role for mesenchyme dynamics in mouse lung branching morphogenesis

P Blanc, K Coste, P Pouchin, JM Azaïs, L Blanchon… - PLoS …, 2012 - journals.plos.org
Mammalian airways are highly ramified tree-like structures that develop by the repetitive
branching of the lung epithelium into the surrounding mesenchyme through reciprocal …

Regulation of the ERK signalling pathway in the developing mouse blastocyst

…, N Allègre, L Valverde Estrella, P Pouchin… - …, 2019 - journals.biologists.com
Activation of the ERK signalling pathway is essential for the differentiation of the inner cell
mass (ICM) during mouse preimplantation development. We show here that ERK …

Spatio-temporal requirements for transposable element piRNA-mediated silencing during Drosophila oogenesis

…, E Theron, C Goriaux, P Pouchin… - Nucleic acids …, 2014 - academic.oup.com
… the activity of 80 P copies in trans (… P repression was previously established using P-lacZ
enhancer-trap transgenes (34). Telomeric P-lacZ inserted in TAS can repress a homologous P-…

[HTML][HTML] sRNAPipe: a Galaxy-based pipeline for bioinformatic in-depth exploration of small RNAseq data

R Pogorelcnik, C Vaury, P Pouchin, S Jensen… - Mobile DNA, 2018 - Springer
… For piRNAs mapping TEs, the ping-pong signature is analysed for each TE and a sum of all
overlaps, the sum of 10-nt-overlaps, the mean, the standard deviation, the z-score and the p-…

Jak-Stat pathway induces Drosophila follicle elongation by a gradient of apical contractility

H Alegot, P Pouchin, O Bardot, V Mirouse - Elife, 2018 - elifesciences.org
10.7554/eLife.32943.001 Tissue elongation and its control by spatiotemporal signals is a
major developmental question. Currently, it is thought that Drosophila ovarian follicular …

The interplay between the Argonaute proteins Piwi and Aub within Drosophila germarium is critical for oogenesis, piRNA biogenesis and TE silencing

E Théron, S Maupetit-Mehouas, P Pouchin… - Nucleic Acids …, 2018 - academic.oup.com
… In Aub-depleted flies, Piwi level is high all along the A/P axis of the germarium where no …
(B) The graph represents the mean intensity of Piwi inside the nuclei along the A/P axis of the …

Oriented basement membrane fibrils provide a memory for F-actin planar polarization via the Dystrophin-Dystroglycan complex during tissue elongation

…, H Alégot, C Fritsch, A Isabella, P Pouchin… - …, 2020 - journals.biologists.com
How extracellular matrix contributes to tissue morphogenesis is still an open question. In the
Drosophila ovarian follicle, it has been proposed that after Fat2-dependent planar …

[HTML][HTML] A new bio imagery user-friendly tool for automatic morphometry measurement on muscle cell cultures and histological sections

A Brun, G Mougeot, P Denis, ML Collin, P Pouchin… - Scientific Reports, 2024 - nature.com
… 1646 myotubes in CTRL and IGF1 condition respectively, *p < 0.05). One-way ANOVA with
… of 15 images per condition were enough to unravel significant myotube atrophy (p < 0.05). …