Epidemiologists in the Brain Tumor Epidemiology Consortium (BTEC) have prioritized areas
for further research. Although many risk factors have been examined over the past several …

Survival for childhood cancer has increased dramatically over the last 40 years with 5-year
survival rates now approaching 80%. For many diagnostic groups, rapid increases in survival …

The 600% increase in medical radiation exposure to the US population since 1980 has
provided immense benefit, but increased potential future cancer risks to patients. Most of the …

Background Although CT scans are very useful clinically, potential cancer risks exist from
associated ionising radiation, in particular for children who are more radiosensitive than adults. …

In an analysis of 31,717 cancer cases and 26,136 cancer-free controls from 13 genome-wide
association studies, we observed large chromosomal abnormalities in a subset of clones in …

… P value <5.0 × 10 −8 were considered for SMR analysis. We set a threshold for the SMR test
of P … correction for 473 tests (473 probes with a top eQTL P < 5.0 × 10 −8 across the 13 loci, …

Although exposure to moderate-to-high doses of ionizing radiation is the only established
environmental risk factor for brain and CNS tumors, it is not clear whether this relationship …

While the etiology of most childhood cancers is largely unknown, epidemiologic studies
have consistently found an association between exposure to medical radiation during …

Gliomas account for approximately 80 % of all primary malignant brain tumors and, despite
improvements in clinical care over the last 20 years, remain among the most lethal tumors, …

Rapid innovations in radiation therapy techniques have resulted in an urgent need for risk
projection models for second cancer risks from high-dose radiation exposure, because direct …