User profiles for P. Schanda

Paul Schanda

Institute of Science and Technology Austria
Verified email at ist.ac.at
Cited by 6377

Studying dynamics by magic-angle spinning solid-state NMR spectroscopy: Principles and applications to biomolecules

P Schanda, M Ernst - Progress in nuclear magnetic resonance …, 2016 - Elsevier
… Note that in contrast to liquid-state NMR off-diagonal contributions ( pp ′ ) to the
angular correlation functions are also important and have to be taken into account. For simple …

Perturbations of native membrane protein structure in alkyl phosphocholine detergents: a critical assessment of NMR and biophysical studies

…, ERS Kunji, G Veglia, TA Cross, P Schanda - Chemical …, 2018 - ACS Publications
Membrane proteins perform a host of vital cellular functions. Deciphering the molecular
mechanisms whereby they fulfill these functions requires detailed biophysical and structural …

SOFAST-HMQC experiments for recording two-dimensional deteronuclear correlation spectra of proteins within a few seconds

P Schanda, Ē Kupče, B Brutscher - Journal of biomolecular NMR, 2005 - Springer
Fast multidimensional NMR with a time resolution of a few seconds provides a new tool for
high throughput screening and site-resolved real-time studies of kinetic molecular processes …

Very fast two-dimensional NMR spectroscopy for real-time investigation of dynamic events in proteins on the time scale of seconds

P Schanda, B Brutscher - Journal of the American Chemical …, 2005 - ACS Publications
We demonstrate for different protein samples that 2D 1 H− 15 N correlation NMR spectra can
be recorded in a few seconds of acquisition time using a new band-selective optimized flip-…

Fast-pulsing longitudinal relaxation optimized techniques: enriching the toolbox of fast biomolecular NMR spectroscopy

P Schanda - Progress in Nuclear Magnetic Resonance …, 2009 - Elsevier
… that, unlike in many other spectroscopic techniques, the spectroscopically active and observable
groups are abundant: each of the hundreds of NMR-active nuclei ( 1 H, 13 C, 15 N, 31 P

[HTML][HTML] Structural basis of NINJ1-mediated plasma membrane rupture in cell death

…, P Schanda, T Maier, C Perez, C Sieben, P Broz… - Nature, 2023 - nature.com
Eukaryotic cells can undergo different forms of programmed cell death, many of which
culminate in plasma membrane rupture as the defining terminal event 1 , 2 , 3 , 4 , 5 , 6 – 7 . …

A set of BEST triple-resonance experiments for time-optimized protein resonance assignment

E Lescop, P Schanda, B Brutscher - Journal of magnetic resonance, 2007 - Elsevier
… bi-directional BEST H–N–CA, H–N–CO, and H–N–CB pulse sequences is presented that
extends the BEST concept introduced recently for fast multidimensional protein NMR [Schanda

Speeding up three-dimensional protein NMR experiments to a few minutes

P Schanda, H Van Melckebeke… - Journal of the American …, 2006 - ACS Publications
We demonstrate for different protein samples that three-dimensional HNCO and HNCA
correlation spectra may be recorded in a few minutes acquisition time using the band-selective …

[PDF][PDF] A Proton‐Detected 4D Solid‐State NMR Experiment for Protein Structure Determination

M Huber, S Hiller, P Schanda, M Ernst… - …, 2011 - academia.edu
Owing to recent advances in instrumentation, methodology and sample-preparation techniques,
solid-state NMR spectroscopy is providing unique insights into biological structures at …

Quantitative analysis of protein backbone dynamics in microcrystalline ubiquitin by solid-state NMR spectroscopy

P Schanda, BH Meier, M Ernst - Journal of the American Chemical …, 2010 - ACS Publications
… There are also 10 residues where six experimental observables are available, but for which
the extended model-free treatment is rejected by the p value < 0.05 criterion. The p value in …