Activated stat-3 in melanoma

JL Messina, H Yu, AI Riker, PN Munster… - Cancer …, 2008 - journals.sagepub.com
… have demonstrated that the Src-Stat pathway may play an important role in melanoma. We
examined the expression of phosphorylated Stat-3 (pStat-3), activated Stat-1 (pStat-1) and …

Aloin reduces inflammatory gene iNOS via inhibition activity and p-STAT-1 and NF-κB

W Lee, S Yang, C Lee, EK Park, KM Kim, SK Ku… - Food and Chemical …, 2019 - Elsevier
Aloin is the major anthraquinone glycoside obtained from the Aloe species and exhibits anti-inflammatory
and anti-oxidative activities. Here, we aimed to determine the effects of aloin …

The miR‐3127‐5p/pSTAT 3 axis up‐regulates PD‐L1 inducing chemoresistance in non‐small‐cell lung cancer

D Tang, D Zhao, Y Wu, R Yao, L Zhou… - Journal of cellular …, 2018 - Wiley Online Library
… promotes pSTAT 3 to induce the expression of PD ‐L1; micro RNA ‐3127‐5p promotes STAT
3 phosphorylation through suppressing autophagy, and autophagy could retaine pSTAT 3 …

Vitamin D regulates claudin-2 and claudin-4 expression in active ulcerative colitis by p-Stat-6 and Smad-7 signaling

V Domazetovic, T Iantomasi, AG Bonanomi… - International Journal of …, 2020 - Springer
… This study shows an increase in the levels of p-Stat-6 in I tract of mucosal biopsies taken
from the colon of patients with active UC with respect to NI tract. This increase in …

Role of RAF/MEK/ERK pathway, pSTAT‐3 and Mcl‐1 in sorafenib activity in human pancreatic cancer cell lines

P Ulivi, C Arienti, D Amadori, F Fabbri… - Journal of cellular …, 2009 - Wiley Online Library
… In our experimental models p-STAT-3 inhibition was higher in the most sensitive t3m4 and …
a role of STAT-3 in determining the activity of sorafenib. Moreover, p-STAT-3 inhibition in t3m4 …

[HTML][HTML] Avicin D selectively induces apoptosis and downregulates p-STAT-3, bcl-2, and survivin in cutaneous T-cell lymphoma cells

C Zhang, B Li, AS Gaikwad, V Haridas, Z Xu… - Journal of investigative …, 2008 - Elsevier
… decreased expression of p-STAT-3 (but not STAT-3) in … p-STAT-3 protein may be involved
in avicin D-induced apoptosis of CTCL cells. However, the mechanisms of reducing p-STAT

[PDF][PDF] Snapshot: Jak-stat signaling

C Mertens, JE Darnell Jr - Cell, 2007 - core.ac.uk
… of a conserved motif (L)P(M) SP in the STAT C terminus (yellow dot). Dissociation from
DNA allows dephosphorylation of STATs by nuclear protein tyrosine phosphatases (N-PTPs), …

Novel herbal medicine C-KOK suppresses the inflammatory gene iNOS via the inhibition of p-STAT-1 and NF-κB

IC Lee, CW Ryu, JS Bae - Biotechnology and Bioprocess Engineering, 2020 - Springer
Cheong-Pye-Ko (CPK) and Kyung-Ok-Ko (KOK) are traditional herbal medicine prescriptions
that have been used in oriental medicine as tonics for pulmonary-related diseases for …

[HTML][HTML] Sox11 expression in astrocytic gliomas: correlation with nestin/c-Met/IDH1-R132H expression phenotypes, p-Stat-3 and survival

P Korkolopoulou, G Levidou, EA El-Habr… - British journal of …, 2013 - nature.com
… Sox11 immunoreactivity was identified in all tumours irrespective of grade, but being correlated
with p-STAT-3. Three out of seven cases showed partial Sox11 promoter methylation. In> …

VEGF receptors on chronic lymphocytic leukemia (CLL) B cells interact with STAT 1 and 3: implication for apoptosis resistance

YK Lee, TD Shanafelt, ND Bone, AK Strege, DF Jelinek… - Leukemia, 2005 - nature.com
… (p)-STAT-1 and p-STAT-3, VEGF-R1/2 are physically associated with p-STAT-1 and p-STAT-3,
and p-STAT-3 (but not p-STAT-1… and perinuclear translocation of STAT 3 through receptor-…