[HTML][HTML] ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques
…, L Rose, S Morris, C Powers, J Lovaglio, PW Hanley… - Nature, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in December
2019 1, 2 and is responsible for the coronavirus disease 2019 (COVID-19) pandemic 3. …
2019 1, 2 and is responsible for the coronavirus disease 2019 (COVID-19) pandemic 3. …
[HTML][HTML] Respiratory disease in rhesus macaques inoculated with SARS-CoV-2
…, B Brumbaugh, VA Avanzato, R Rosenke, PW Hanley… - Nature, 2020 - nature.com
An outbreak of coronavirus disease 2019 (COVID-19), which is caused by a novel coronavirus
(named SARS-CoV-2) and has a case fatality rate of approximately 2%, started in Wuhan (…
(named SARS-CoV-2) and has a case fatality rate of approximately 2%, started in Wuhan (…
[HTML][HTML] Clinical benefit of remdesivir in rhesus macaques infected with SARS-CoV-2
…, L Pérez-Pérez, A Okumura, J Lovaglio, PW Hanley… - Nature, 2020 - nature.com
Effective therapies to treat coronavirus disease 2019 (COVID-19) are urgently needed. While
many investigational, approved, and repurposed drugs have been suggested as potential …
many investigational, approved, and repurposed drugs have been suggested as potential …
Intranasal ChAdOx1 nCoV-19/AZD1222 vaccination reduces viral shedding after SARS-CoV-2 D614G challenge in preclinical models
…, F Amanat, F Krammer, PW Hanley… - Science translational …, 2021 - science.org
ChAdOx1 nCoV-19/AZD1222 is an approved adenovirus-based vaccine for severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) currently being deployed globally. Previous …
respiratory syndrome coronavirus 2 (SARS-CoV-2) currently being deployed globally. Previous …
VSV-EBOV rapidly protects macaques against infection with the 2014/15 Ebola virus outbreak strain
…, SJ Robertson, E Haddock, F Feldmann, PW Hanley… - Science, 2015 - science.org
The latest Ebola virus (EBOV) epidemic spread rapidly through Guinea, Sierra Leone, and
Liberia, creating a global public health crisis and accelerating the assessment of …
Liberia, creating a global public health crisis and accelerating the assessment of …
SARS-CoV-2 Omicron BA. 1 and BA. 2 are attenuated in rhesus macaques as compared to Delta
…, A Okumura, F Feldmann, J Lovaglio, PW Hanley… - Science …, 2022 - science.org
Since the emergence of SARS-CoV-2, five different variants of concern (VOCs) have been
identified: Alpha, Beta, Gamma, Delta, and Omicron. Because of confounding factors in the …
identified: Alpha, Beta, Gamma, Delta, and Omicron. Because of confounding factors in the …
[PDF][PDF] A single intranasal dose of chimpanzee adenovirus-vectored vaccine protects against SARS-CoV-2 infection in rhesus macaques
…, J Callison, RE Chen, J Lovaglio, PW Hanley… - Cell Reports …, 2021 - cell.com
The deployment of a vaccine that limits transmission and disease likely will be required to
end the coronavirus disease 2019 (COVID-19) pandemic. We recently described the …
end the coronavirus disease 2019 (COVID-19) pandemic. We recently described the …
A single dose of ChAdOx1 MERS provides protective immunity in rhesus macaques
…, T Bushmaker, RJ Fischer, A Okumura, PW Hanley… - Science …, 2020 - science.org
Developing a vaccine to protect against the lethal effects of the many strains of coronavirus
is critical given the current global pandemic. For Middle East respiratory syndrome …
is critical given the current global pandemic. For Middle East respiratory syndrome …
[HTML][HTML] A DNA-based vaccine protects against Crimean-Congo haemorrhagic fever virus disease in a Cynomolgus macaque model
…, KS Appelberg, K Meade-White, PW Hanley… - Nature …, 2021 - nature.com
There is currently no specific prophylaxis or vaccine against Crimean-Congo haemorrhagic
fever virus (CCHFV). Crimean-Congo haemorrhagic fever (CCHF) is a severe febrile illness …
fever virus (CCHFV). Crimean-Congo haemorrhagic fever (CCHF) is a severe febrile illness …
[HTML][HTML] Use of favipiravir to treat Lassa virus infection in macaques
…, H Feldmann, JB Westover, PW Hanley… - Emerging infectious …, 2018 - ncbi.nlm.nih.gov
Lassa virus, the cause of Lassa fever in humans, is endemic to West Africa. Treatment of Lassa
fever is primarily supportive, although ribavirin has shown limited efficacy if administered …
fever is primarily supportive, although ribavirin has shown limited efficacy if administered …