We aggregated coding variant data for 81,412 type 2 diabetes cases and 370,832 controls
of diverse ancestry, identifying 40 coding variant association signals (P < 2.2 × 10 −7 ); of …

… For each variant in this subset, we provided Swiss with the minimum unconditional P value
across all traits. The clumping procedure starts with the variant with the smallest P value, …

… However, relative to the Undernourished epigenetic profiles, we observed a significant
increase in activated marks (p < 0.0001) and a decline in suppressed marks (p < 0.0001) in the …

… (n = 27) in cognition (p = 0.044) and language (p = 0.020) domains (adjusted for maternal
… significance at p < 0.05, $ significance p < 0.05 value adjusted for maternal baseline B12 …

Background The Pune Maternal Nutrition Study (PMNS) was established to prospectively
study the relationship of maternal nutrition to fetal growth and later cardiometabolic risk in the …

… For SKAT, we used asymptotic theory p-values, which conformed well to p-values estimated
by permutation (data not shown). For the CMC, we estimated p-values based on 10,000 …

Bayesian strategies for planning and analyzing clinical trials have become a viable choice,
especially in rare diseases where drug development faces many challenges and …

Background Vitamin B-12 deficiency is often considered synonymous with pernicious
anemia, a rare condition in which severe malabsorption of the vitamin requires high-dose …

OBJECTIVE India is a double world capital of early-life undernutrition and type 2 diabetes.
We aimed to characterize life course growth and metabolic trajectories in those developing …

Our objective was to investigate associations of body size (birth weight and body mass
index (BMI)) and growth in height, body fat (adiposity) and lean mass during childhood and …