Mechanosensory hair cells are essential for audition in vertebrates, and in many species,
have the capacity for regeneration when damaged. Regeneration is robust in the fish lateral …

The deposition and accumulation of amyloid-β-peptide (Aβ) in the brain are considered a
sine qua non for Alzheimer's disease. The experimental delivery of fibrilized Aβ serves as a …

Vasopressin regulates water excretion, in part, by controlling the abundances of the water
channel aquaporin-2 (AQP2) protein and regulatory proteins in the renal collecting duct. To …

Vasopressin-mediated regulation of renal water excretion is defective in a variety of water
balance disorders in humans. It occurs in part through long-term mechanisms that regulate the …

The lateral line system comprises an array of mechanosensory organs, the neuromasts,
distributed over the body surface. Each neuromast consists of a patch of mechanosensory hair …

The sensory organs of the zebrafish lateral‐line system (neuromasts) originate from migrating
primordia that move along precise pathways. The posterior primordium, which deposits …

Vasopressin controls osmotic water transport in the renal collecting duct through regulation
of aquaporin-2 (AQP2). We carried out bioinformatic analysis of quantitative proteomic data …

The peptide hormone arginine vasopressin (AVP) plays a critical role in regulating salt and
water transport in the mammalian kidney. Recent studies have also demonstrated that AVP …

The mouse mpkCCD cell line is a continuous cultured epithelial cell line with characteristics
of renal collecting duct principal cells. This line is widely used to study epithelial transport …

Protein carbamylation is a post-translational modification that can occur in the presence of
urea. In solution, urea is in equilibrium with ammonium cyanate, and carbamylation occurs …