Macrophages are best known for their protective search and destroy functions against
invading microorganisms. These processes are commonly known as chemotaxis and …

Cells have evolved multiple mechanisms to apprehend and adapt finely to their environment.
Here we report a new cellular ability, which we term “curvotaxis” that enables the cells to …

During metastasis to distant sites, tumor cells migrate to blood vessels. In vivo, breast tumor
cells utilize a specialized mode of migration known as streaming, where a linear assembly of …

Rho GTPases are key signal transducer elements activated in T cells by both chemokine
and antigen receptors. These two signalling pathways control the two main functions of T …

The proper integration of biophysical cues from the cell vicinity is crucial for cells to maintain
homeostasis, cooperate with other cells within the tissues, and properly fulfill their biological …

How biophysical cues can control tissue morphogenesis is a central question in biology and
for the development of efficient tissue engineering strategies. Recent data suggest that …

Forkhead box O (FOXO) transcription factors favor both T cell quiescence and trafficking
through their control of the expression of genes involved in cell cycle progression, adhesion, …

Featured Application The evaluation of the behavior of cultured cells on substrates with
controlled topographies can contribute significantly to the optimization of biomaterials for …

Macrophage phagocytosis is a strikingly flexible process central to pathogen clearance and
is an attractive target for the development of anti-cancer immunotherapies. To harness the …

theses.fr – Pablo Rougerie , Caractérisation fonctionnelle de FINROD, un nouvel inhibiteur
atypique des Rho GTPases dans l’activation et la migration des lymphocytes T Connexion …