Action potentials in many central neurons are followed by a prolonged afterhyperpolarization
(AHP) that influences firing frequency and affects neuronal integration. In hippocampal …

Evaluation of infarct volumes and infiltrating immune cell populations in mice after middle
cerebral artery occlusion (MCAO) strongly implicates a mixture of both pathogenic and …

Biologic sex influences many variables that are important to brain health in general, and to
stroke or cerebral ischemia in particular, such as general health status, cerebrovascular …

Small conductance Ca 2+ ‐activated K + channels (SK channels) contribute to the long
lasting afterhyperpolarization (AHP) that follows an action potential in many central neurones. …

Episodic ataxia type-1 (EA1) is a dominant human neurological disorder characterized by
stress-induced attacks of ataxia. EA1 is caused by mutations in the voltage-gated potassium …

Sex steroids are essential for reproduction and development in animals and humans, and
sex steroids also play an important role in neuroprotection following brain injury. New data …

We have demonstrated, for the first time that microvesicles, a sub-type of extracellular
vesicles (EVs) derived from hCMEC/D3: a human brain endothelial cell (BEC) line transfer …

Biologic sex and sex steroids are important factors in clinical and experimental stroke and
traumatic brain injury (TBI). Laboratory data strongly show that progesterone treatment after …

Emerging evidence suggests that renal endothelial function may be altered in ischemia-reperfusion
injury. Acute kidney injury is sexually dimorphic, and estrogen protects renal tubular …

Every year in the United States, millions of individuals incur ischemic brain injury from stroke,
cardiac arrest, or traumatic brain injury (TBI). These forms of acquired brain injury can lead …