[HTML][HTML] Prophylactic intranasal administration of a TLR2/6 agonist reduces upper respiratory tract viral shedding in a SARS-CoV-2 challenge ferret model
PC Proud, D Tsitoura, RJ Watson, BY Chua… - …, 2021 - thelancet.com
Background The novel human coronavirus SARS-CoV-2 is a major ongoing global threat
with huge economic burden. Like all respiratory viruses, SARS-CoV-2 initiates infection in the …
with huge economic burden. Like all respiratory viruses, SARS-CoV-2 initiates infection in the …
[HTML][HTML] Standardised quantitative assays for anti-SARS-CoV-2 immune response used in vaccine clinical trials by the CEPI Centralized Laboratory Network: a …
…, A Fabie, M Daugan, ST Khan, P Proud… - The Lancet …, 2024 - thelancet.com
Background Accurate quantitation of immune markers is crucial for ensuring reliable
assessment of vaccine efficacy against infectious diseases. This study was designed to confirm …
assessment of vaccine efficacy against infectious diseases. This study was designed to confirm …
[HTML][HTML] Immunologic resilience and COVID-19 survival advantage
…, PB Polk, MA Pomager, KJ Preston, KC Proud… - Journal of Allergy and …, 2021 - Elsevier
Background The risk of severe coronavirus disease 2019 (COVID-19) varies significantly
among persons of similar age and is higher in males. Age-independent, sex-biased differences …
among persons of similar age and is higher in males. Age-independent, sex-biased differences …
Distinct signaling events downstream of mTOR cooperate to mediate the effects of amino acids and insulin on initiation factor 4E-binding proteins
…, M Murakami, S Yamanaka, CG Proud - … and cellular biology, 2005 - Taylor & Francis
Signaling through the mammalian target of rapamycin (mTOR) controls cell size and growth
as well as other functions, and it is a potential therapeutic target for graft rejection, certain …
as well as other functions, and it is a potential therapeutic target for graft rejection, certain …
The mTOR pathway in the control of protein synthesis
… C: mTOR regulates by the transcription of rRNA (in the nucleolus) and the translation of r-…
41 Proud CG. Control of the elongation phase of protein synthesis. In: Translational Control …
41 Proud CG. Control of the elongation phase of protein synthesis. In: Translational Control …
Standardization and Harmonization of SARS-COV-2 Assays Offered by the CEPI Centralized Laboratory Network in Support for Vaccine Clinical Trials
…, A Fabie, M Daugan, ST Khan, P Proud… - 2023 - papers.ssrn.com
Background: Accurate quantitation of immune markers is critical for ensuring reliable
assessment of vaccines efficacy against infectious diseases. This report presents the …
assessment of vaccines efficacy against infectious diseases. This report presents the …
[HTML][HTML] mTOR direct interactions with Rheb-GTPase and raptor: sub-cellular localization using fluorescence lifetime imaging
Background The mammalian target of rapamycin (mTOR) signalling pathway has a key role
in cellular regulation and several diseases. While it is thought that Rheb GTPase regulates …
in cellular regulation and several diseases. While it is thought that Rheb GTPase regulates …
[PDF][PDF] The annual awards of the aerospace medical association
RM STANLEY, C PAMELA - Aviation, space, and environmental medicine, 2006 - Citeseer
… Military aviators may be proud of their physical training, but expect no improvement of
mission effectiveness as a result of better physical training. A diet and fitness regimen tailored to …
mission effectiveness as a result of better physical training. A diet and fitness regimen tailored to …
Mutation in the gene responsible for cystic fibrosis and predisposition to chronic rhinosinusitis in the general population
…, J Kim, RC Rubenstein, A Togias, D Proud… - Jama, 2000 - jamanetwork.com
ContextChronic rhinosinusitis (CRS) is a common condition in the US general population,
yet little is known about its underlying molecular cause. Chronic rhinosinusitis is a consistent …
yet little is known about its underlying molecular cause. Chronic rhinosinusitis is a consistent …
Learning from our colleagues 'across the pond'
…, S Tiplady, P de Gravelles, C Proud - Nursing and …, 2016 - magonlinelibrary.com
Care home placements in the UK can leave student nurses under-equipped for the care
home nurse role. In this article, Juliana Thompson et al describe how student placements at …
home nurse role. In this article, Juliana Thompson et al describe how student placements at …