User profiles for Pamela VandeVord

Pamela VandeVord

Virginia Tech
Verified email at vt.edu
Cited by 5088

Blast induces oxidative stress, inflammation, neuronal loss and subsequent short-term memory impairment in rats

HJ Cho, VSSS Sajja, PJ Vandevord, YW Lee - Neuroscience, 2013 - Elsevier
Molecular and cellular mechanisms of brain injury after exposure to blast overpressure (BOP)
are not clearly known. The present study hypothesizes that pro-oxidative and pro-…

Evaluation of the biocompatibility of a chitosan scaffold in mice

PJ VandeVord, HWT Matthew… - … Research: An Official …, 2002 - Wiley Online Library
Chitosan scaffolds appear to be suitable for a variety of tissue engineering applications. This
study addressed the biocompatibility of chitosan in a mouse implantation model. Porous …

Intracranial pressure increases during exposure to a shock wave

…, CA Bir, DV Ritzel, PJ VandeVord - Journal of …, 2011 - liebertpub.com
Traumatic brain injuries (TBI) caused by improvised explosive devices (IEDs) affect a significant
percentage of surviving soldiers wounded in Iraq and Afghanistan. The extent of a blast …

Skull flexure as a contributing factor in the mechanism of injury in the rat when exposed to a shock wave

…, B Mathie, C Bir, D Ritzel, P VandeVord - Annals of biomedical …, 2011 - Springer
The manner in which energy from an explosion is transmitted into the brain is currently a
highly debated topic within the blast injury community. This study was conducted to investigate …

Traumatic white matter injury and glial activation: from basic science to clinics

Z Kou, PJ VandeVord - Glia, 2014 - Wiley Online Library
An improved understanding and characterization of glial activation and its relationship with
white matter injury will likely serve as a novel treatment target to curb post injury inflammation …

Blast-induced tinnitus and hearing loss in rats: behavioral and imaging assays

…, P Pierozynski, Z Kou, Y Shen, P VandeVord… - Journal of …, 2012 - liebertpub.com
The current study used a rat model to investigate the underlying mechanisms of blast-induced
tinnitus, hearing loss, and associated traumatic brain injury (TBI). Seven rats were used to …

Promotion of osteogenesis in tissue‐engineered bone by pre‐seeding endothelial progenitor cells‐derived endothelial cells

H Yu, PJ VandeVord, W Gong, B Wu… - Journal of …, 2008 - Wiley Online Library
In addition to a biocompatible scaffold and an osteogenic cell population, tissue‐engineered
bone requires an appropriate vascular bed to overcome the obstacle of nutrient and oxygen …

[HTML][HTML] Enduring deficits in memory and neuronal pathology after blast-induced traumatic brain injury

…, F Ghoddoussi, MP Galloway, PJ VandeVord - Scientific reports, 2015 - nature.com
Few preclinical studies have assessed the long-term neuropathology and behavioral deficits
after sustaining blast-induced neurotrauma (BINT). Previous studies have shown extensive …

Improved tissue-engineered bone regeneration by endothelial cell mediated vascularization

H Yu, PJ VandeVord, L Mao, HW Matthew, PH Wooley… - Biomaterials, 2009 - Elsevier
Natural bone growth greatly depends on the precedent vascular network that supplies
oxygen and essential nutrients and removes metabolites. Likewise, it is crucial for tissue-…

[HTML][HTML] Role of glia in memory deficits following traumatic brain injury: biomarkers of glia dysfunction

VSSS Sajja, N Hlavac, PJ VandeVord - Frontiers in integrative …, 2016 - frontiersin.org
Historically, glial cells have been recognized as a structural component of the brain. However,
it has become clear that glial cells are intimately involved in the complexities of neural …