User profiles for Pankaj Baral

Pankaj Baral, Ph.D.

Assistant Professor, Kansas State University
Verified email at ksu.edu
Cited by 2777

CXCL1 regulates neutrophil homeostasis in pneumonia-derived sepsis caused by Streptococcus pneumoniae serotype 3

S Paudel, P Baral, L Ghimire… - Blood, The Journal …, 2019 - ashpublications.org
Neutrophil migration to the site of bacterial infection is a critical step in host defense.
Exclusively produced in the bone marrow, neutrophil release into the blood is tightly controlled. …

The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation

…, D Farouq, BJ Haas, TL Tickle, JJ Trombetta, P Baral… - Nature, 2017 - nature.com
Type 2 innate lymphoid cells (ILC2s) both contribute to mucosal homeostasis and initiate
pathologic inflammation in allergic asthma. However, the signals that direct ILC2s to promote …

Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells

B Zhang, S Ma, I Rachmin, M He, P Baral, S Choi… - Nature, 2020 - nature.com
Empirical and anecdotal evidence has associated stress with accelerated hair greying (formation
of unpigmented hairs) 1 , 2 , but so far there has been little scientific validation of this …

[HTML][HTML] Staphylococcus aureus produces pain through pore-forming toxins and neuronal TRPV1 that is silenced by QX-314

KJ Blake, P Baral, T Voisin, A Lubkin… - Nature …, 2018 - nature.com
The hallmark of many bacterial infections is pain. The underlying mechanisms of pain
during live pathogen invasion are not well understood. Here, we elucidate key molecular …

Pain and immunity: implications for host defence

P Baral, S Udit, IM Chiu - Nature Reviews Immunology, 2019 - nature.com
Pain is a hallmark of tissue injury, inflammatory diseases, pathogen invasion and neuropathy.
It is mediated by nociceptor sensory neurons that innervate the skin, joints, bones, …

[HTML][HTML] Nociceptor sensory neurons suppress neutrophil and γδ T cell responses in bacterial lung infections and lethal pneumonia

P Baral, BD Umans, L Li, A Wallrapp, M Bist… - Nature medicine, 2018 - nature.com
Lung-innervating nociceptor sensory neurons detect noxious or harmful stimuli and consequently
protect organisms by mediating coughing, pain, and bronchoconstriction. However, the …

[PDF][PDF] Gut-innervating nociceptor neurons regulate Peyer's patch microfold cells and SFB levels to mediate Salmonella host defense

NY Lai, MA Musser, FA Pinho-Ribeiro, P Baral… - Cell, 2020 - cell.com
Gut-innervating nociceptor sensory neurons respond to noxious stimuli by initiating protective
responses including pain and inflammation; however, their role in enteric infections is …

[HTML][HTML] High prevalence of multidrug resistance in bacterial uropathogens from Kathmandu, Nepal

P Baral, S Neupane, BP Marasini, KR Ghimire… - BMC Research …, 2012 - Springer
Background Urinary Tract Infection (UTI) is one of the most common infectious diseases and
people of all age-groups and geographical locations are affected. The impact of disease is …

[HTML][HTML] Evaluation of antibacterial activity of some traditionally used medicinal plants against human pathogenic bacteria

BP Marasini, P Baral, P Aryal, KR Ghimire… - BioMed research …, 2015 - hindawi.com
The worldwide increase of multidrug resistance in both community- and health-care associated
bacterial infections has impaired the current antimicrobial therapy, warranting the search …

Geohelminths: public health significance

…, C Jaide, N Jinawath, P Rotjanapan, P Baral - The Journal of Infection in …, 2014 - jidc.org
The worldwide prevalence of geohelminths and their unique place in evolutionary biology
have attracted research focus. These major soil-transmitted intestinal nematodes that cause …