User profiles for Paolo Provero
 | Paolo ProveroProfessor, University of Turin Verified email at unito.it Cited by 14800 |
[HTML][HTML] Differential co-expression analyses allow the identification of critical signalling pathways altered during tumour transformation and progression
Biological systems respond to perturbations through the rewiring of molecular interactions,
organised in gene regulatory networks (GRNs). Among these, the increasingly high …
organised in gene regulatory networks (GRNs). Among these, the increasingly high …
[HTML][HTML] Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs
Here, we demonstrate that protein-coding RNA transcripts can crosstalk by competing for
common microRNAs, with microRNA response elements as the foundation of this interaction. …
common microRNAs, with microRNA response elements as the foundation of this interaction. …
[HTML][HTML] In vivo identification of tumor-suppressive PTEN ceRNAs in an oncogenic BRAF-induced mouse model of melanoma
We recently proposed that competitive endogenous RNAs (ceRNAs) sequester microRNAs
to regulate mRNA transcripts containing common microRNA recognition elements (MREs). …
to regulate mRNA transcripts containing common microRNA recognition elements (MREs). …
Minimum physical length and the generalized uncertainty principle in string theory
A possible definition of path integrals for string theory is studied, based on a discretized
version of Polyakov's generating functional. The finite resolution of string theory, as opposed to …
version of Polyakov's generating functional. The finite resolution of string theory, as opposed to …
The BioMart community portal: an innovative alternative to large, centralized data repositories
The BioMart Community Portal ( www.biomart.org ) is a community-driven effort to provide a
unified interface to biomedical databases that are distributed worldwide. The portal provides …
unified interface to biomedical databases that are distributed worldwide. The portal provides …
[HTML][HTML] Behavioral and psychological effects of coronavirus disease-19 quarantine in patients with dementia
…, V Laganà, E Rubino, A Vacca, P Provero… - Frontiers in …, 2020 - frontiersin.org
Background In March 2020, the World Health Organization declared a global pandemic due
to the novel coronavirus SARS-CoV-2 and several governments planned a national …
to the novel coronavirus SARS-CoV-2 and several governments planned a national …
EZH2 is essential for glioblastoma cancer stem cell maintenance
…, N Riggi, M Janiszewska, I Radovanovic, P Provero… - Cancer research, 2009 - AACR
Overexpression of the polycomb group protein enhancer of zeste homologue 2 (EZH2)
occurs in diverse malignancies, including prostate cancer, breast cancer, and glioblastoma …
occurs in diverse malignancies, including prostate cancer, breast cancer, and glioblastoma …
[HTML][HTML] A STAT3-mediated metabolic switch is involved in tumour transformation and STAT3 addiction
The pro-oncogenic transcription factor STAT3 is constitutively activated in a wide variety of
tumours that often become addicted to its activity, but no unifying view of a core function …
tumours that often become addicted to its activity, but no unifying view of a core function …
Integrated transcriptional and competitive endogenous RNA networks are cross-regulated in permissive molecular environments
Competitive endogenous (ce)RNAs cross-regulate each other through sequestration of
shared microRNAs and form complex regulatory networks based on their microRNA signature. …
shared microRNAs and form complex regulatory networks based on their microRNA signature. …
Development of Ewing's sarcoma from primary bone marrow–derived mesenchymal progenitor cells
Ewing's sarcoma is a member of Ewing's family tumors (EFTs) and the second most common
solid bone and soft tissue malignancy of children and young adults. It is associated in 85% …
solid bone and soft tissue malignancy of children and young adults. It is associated in 85% …