User profiles for Paolo Uva

Paolo Uva

Clinical Bioinformatics Unit, IRCCS G. Gaslini, Genoa, Italy
Verified email at gaslini.org
Cited by 3116

[HTML][HTML] Gut microbiota markers associated with obesity and overweight in Italian adults

…, V Madau, E Casula, A Deledda, R Cusano, P Uva… - Scientific reports, 2021 - nature.com
In the present study, we characterized the distinctive signatures of the gut microbiota (GM)
from overweight/obese patients (OB), and normal-weight controls (NW), both of Sardinian …

Tools and data services registry: a community effort to document bioinformatics resources

…, SCE Tosatto, V De La Torre, P Uva… - Nucleic acids …, 2016 - academic.oup.com
Life sciences are yielding huge data sets that underpin scientific discoveries fundamental to
improvement in human health, agriculture and the environment. In support of these …

[HTML][HTML] Comparative expression pathway analysis of human and canine mammary tumors

P Uva, L Aurisicchio, J Watters, A Loboda, A Kulkarni… - BMC genomics, 2009 - Springer
Background Spontaneous tumors in dog have been demonstrated to share many features
with their human counterparts, including relevant molecular targets, histological appearance, …

Orione, a web-based framework for NGS analysis in microbiology

…, A Sbardellati, N Soranzo, A Travaglione, P Uva… - …, 2014 - academic.oup.com
End-to-end next-generation sequencing microbiology data analysis requires a diversity of
tools covering bacterial resequencing, de novo assembly, scaffolding, bacterial RNA-Seq, …

Gut microbiota and metabolome alterations associated with Parkinson's disease

…, V Palmas, M Melis, S Pisanu, R Cusano, P Uva… - Msystems, 2020 - Am Soc Microbiol
Parkinson’s disease is a neurodegenerative disorder characterized by the accumulation of
intracellular aggregates of misfolded alpha-synuclein along the cerebral axis. Several studies …

Biosystematics of Reticulitermes termites in Europe: morphological, chemical and molecular data

JL Clément, AG Bagnères, P Uva, L Wilfert, A Quintana… - Insectes sociaux, 2001 - Springer
In Europe the most abundant naturally residing termite is the subterranean genus Reticulitermes
(Rhinotermitidae). Six phenotypes of Reticulitermes have been identified on the basis …

[HTML][HTML] Portrait of cancer stem cells on colorectal cancer: molecular biomarkers, signaling pathways and miRNAome

…, MC Ninniri, C Carru, A Porcu, G Pira, P Uva… - International journal of …, 2021 - mdpi.com
Colorectal cancer (CRC) is a leading cause of cancer death worldwide, and about 20% is
metastatic at diagnosis and untreatable. Increasing evidence suggests that the heterogeneous …

[HTML][HTML] Exploration of tools for the interpretation of human non-coding variants

N Tabarini, E Biagi, P Uva, E Iovino, T Pippucci… - International Journal of …, 2022 - mdpi.com
The advent of Whole Genome Sequencing (WGS) broadened the genetic variation detection
range, revealing the presence of variants even in non-coding regions of the genome, which …

Monozygotic twins discordant for recessive dystrophic epidermolysis bullosa phenotype highlight the role of TGF-β signalling in modifying disease severity

…, F Cianfarani, A Travaglione, P Uva… - Human molecular …, 2014 - academic.oup.com
Recessive dystrophic epidermolysis bullosa (RDEB) is a genodermatosis characterized by
fragile skin forming blisters that heal invariably with scars. It is due to mutations in the …

[HTML][HTML] Modulatory role of microRNAs in triple negative breast cancer with basal-like phenotype

…, C Arru, MR Muroni, V Rallo, C Carru, P Uva… - Cancers, 2020 - mdpi.com
Simple Summary Triple Negative breast cancer (TNBC) is an aggressive tumor showing high
histological grade, high recurrence, and frequent metastasis, accounting for about 25% of …