The cellular alterations associated with skeletal muscle differentiation share a high degree
of similarity with key phenotypic changes usually ascribed to apoptosis. For example, actin …

Caspase proteases have become the focal point for the development and application of anti‐apoptotic
therapies in a variety of central nervous system diseases. However, this approach …

Small heat shock proteins protect cells from stress presumably by acting as molecular
chaperones. Here we report on the functional characterization of a developmentally regulated, …

Brown adipose tissue (BAT) is an energy-dispensing thermogenic tissue that plays an important
role in balancing energy metabolism. Lineage-tracing experiments indicate that brown …

Ga radioisotopes, including the generator-produced positron-emitting isotope 68 Ga (t 1/2 =
68 min), are of increasing interest for the development of new radiopharmaceuticals. …

The benefits of apoptosis for a multicellular organism are obvious and fit the current dogma
that the maintenance and viability of such organisms are dependent on the selective …

Cardiomyocyte hypertrophy is the cellular response that mediates pathologic enlargement
of the heart. This maladaptation is also characterized by cell behaviors that are typically …

The post-natal heart adapts to stress and overload through hypertrophic growth, a process
that may be pathologic or beneficial (physiologic hypertrophy). Physiologic hypertrophy …

In skeletal muscle development, the genes and regulatory factors that govern the specification
of myocytes are well described. Despite this knowledge, the mechanisms that regulate the …

Background The root system is vital to plant growth and survival. Therefore, genetic
improvement of the root system is beneficial for developing stress-tolerant and improved plant …