[HTML][HTML] Breaking spore dormancy in budding yeast transforms the cytoplasm and the solubility of the proteome
S Plante, KM Moon, P Lemieux, LJ Foster… - PLoS Biology, 2023 - journals.plos.org
The biophysical properties of the cytoplasm are major determinants of key cellular
processes and adaptation. Many yeasts produce dormant spores that can withstand extreme …
processes and adaptation. Many yeasts produce dormant spores that can withstand extreme …
Dissection of the role of a Src homology 3 domain in the evolution of binding preference of paralogous proteins
Protein–protein interactions (PPIs) drive many cellular processes. Some interactions are
directed by Src homology 3 (SH3) domains that bind proline-rich motifs on other proteins. The …
directed by Src homology 3 (SH3) domains that bind proline-rich motifs on other proteins. The …
Cryptic genetic variation shapes the fate of gene duplicates in a protein interaction network
S Dibyachintan, AK Dube, D Bradley, P Lemieux… - bioRxiv, 2024 - biorxiv.org
Paralogous genes are often redundant for long periods of time before they diverge in function.
While their functions are preserved, paralogous proteins can accumulate mutations that, …
While their functions are preserved, paralogous proteins can accumulate mutations that, …
Exit of spore dormancy transforms the yeast cytoplasm and the solubility of its proteome
The biophysical properties of the cytoplasm are major determinants of key cellular processes
and adaptation. Yeasts produce dormant spores that can withstand extreme conditions. We …
and adaptation. Yeasts produce dormant spores that can withstand extreme conditions. We …
[PDF][PDF] Toeholder: a software for automated design and in silico validation of toehold riboswitches
AF Cisneros, FD Rouleau, C Bautista, P Lemieux… - bioRxiv, 2021 - peerj.com
Synthetic biology aims to engineer biological circuits, which often involve gene expression.
A particularly promising group of regulatory elements are riboswitches because of their …
A particularly promising group of regulatory elements are riboswitches because of their …
[HTML][HTML] A novel approach for engineering biological systems by interfacing computer science with synthetic biology
S Melamed - Peer Community in Genomics, 2022 - genomics.peercommunityin.org
A recommendation of: Angel F. Cisneros, François D. Rouleau, Carla Bautista, Pascale
Lemieux, Nathan Dumont-Leblond Toeholder: a Software for Automated Design and In Silico …
Lemieux, Nathan Dumont-Leblond Toeholder: a Software for Automated Design and In Silico …
Cutting edge: Ly49A inhibits TCR/CD3-induced apoptosis and IL-2 secretion
J Roger, A Chalifour, S Lemieux… - The Journal of …, 2001 - journals.aai.org
To evaluate the importance of Ly49A on TCR-induced cellular events, we established clones
of the 1F2 T cell hybridoma expressing either Ly49A or a chimeric version, Ly49A/H, where …
of the 1F2 T cell hybridoma expressing either Ly49A or a chimeric version, Ly49A/H, where …
Helix-length compensation studies reveal the adaptability of the VS ribozyme architecture
J Lacroix-Labonte, N Girard, S Lemieux… - Nucleic acids …, 2012 - academic.oup.com
Compensatory mutations in RNA are generally regarded as those that maintain base pairing,
and their identification forms the basis of phylogenetic predictions of RNA secondary …
and their identification forms the basis of phylogenetic predictions of RNA secondary …
Impact of waist circumference on the relationship between blood pressure and insulin: the Quebec Health Survey
P Poirier, I Lemieux, P Mauriege, E Dewailly… - …, 2005 - Am Heart Assoc
Hyperinsulinemia has been suggested to be involved in the etiology of obesity-associated
hypertension. The objective of the present study was to quantify, in a population-based study, …
hypertension. The objective of the present study was to quantify, in a population-based study, …
Adiponectinemia in visceral obesity: impact on glucose tolerance and plasma lipoprotein and lipid levels in men
The present study examined the associations between a major adipokine, adiponectin, and
adiposity indices as well as metabolic risk variables in a sample of 190 untreated …
adiposity indices as well as metabolic risk variables in a sample of 190 untreated …