User profiles for Pat Levitt

Pat Levitt

Provost Professor of Neurogenetics
Verified email at med.usc.edu
Cited by 39523

How the timing and quality of early experiences influence the development of brain architecture

SE Fox, P Levitt, CA Nelson III - Child development, 2010 - Wiley Online Library
Early life events can exert a powerful influence on both the pattern of brain architecture and
behavioral development. In this study a conceptual framework is provided for considering …

Structural and functional maturation of the developing primate brain

P Levitt - The Journal of pediatrics, 2003 - Elsevier
Descriptive studies have established that the developmental events responsible for the
assembly of neural systems and circuitry are conserved across mammalian species. However, …

Requirement of a corepressor for Dr1-mediated repression of transcription.

…, K Eagelson, D Landsman, P Levitt… - Genes & …, 1996 - genesdev.cshlp.org
A Dr1-associated polypeptide (DRAP1) was isolated from HeLa cells and found to function
as a corepressor of transcription. Corepressor function requires an interaction between …

[HTML][HTML] Childhood adversity, mental health, and oxidative stress: A pilot study

SR Horn, LD Leve, P Levitt, PA Fisher - PloS one, 2019 - journals.plos.org
Childhood adversity is a potent risk factor for mental health conditions via disruptions to stress
response systems. Dysregulations in oxidative stress systems have been associated with …

Autism spectrum disorders: developmental disconnection syndromes

DH Geschwind, P Levitt - Current opinion in neurobiology, 2007 - Elsevier
Autism is a common and heterogeneous childhood neurodevelopmental disorder. Analogous
to broad syndromes such as mental retardation, autism has many etiologies and should …

Schizophrenia as a disorder of neurodevelopment

DA Lewis, P Levitt - Annual review of neuroscience, 2002 - annualreviews.org
▪ Abstract A combination of genetic susceptibility and environmental perturbations appear to
be necessary for the expression of schizophrenia. In addition, the pathogenesis of the …

Transcriptional landscape of the prenatal human brain

…, RF Hevner, H Huang, AR Jones, JA Knowles, P Levitt… - Nature, 2014 - nature.com
The anatomical and functional architecture of the human brain is mainly determined by prenatal
transcriptional processes. We describe an anatomically comprehensive atlas of the mid-…

Evaluation, diagnosis, and treatment of gastrointestinal disorders in individuals with ASDs: a consensus report

…, H Jyonouchi, K Kooros, R Kushak, P Levitt… - …, 2010 - publications.aap.org
Autism spectrum disorders (ASDs) are common and clinically heterogeneous neurodevelopmental
disorders. Gastrointestinal disorders and associated symptoms are commonly …

[HTML][HTML] Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex

K Mirnics, FA Middleton, A Marquez, DA Lewis, P Levitt - Neuron, 2000 - cell.com
Microarray expression profiling of prefrontal cortex from matched pairs of schizophrenic and
control subjects and hierarchical data analysis revealed that transcripts encoding proteins …

Immunoperoxidase localization of glial fibrillary acidic protein in radial glial cells and astrocytes of the developing rhesus monkey brain

P Levitt, P Rakic - Journal of Comparative Neurology, 1980 - Wiley Online Library
Peroxidase‐antiperoxidase (PAP) immunohistochemical staining, utilizing a specific antibody
to the glial fibrillary acidic protein (GFA), was employed to analyze gliogenesis in the …