A new insight into the dissociating effect of strontium on bone resorption and formation

…, JM Nedelec, D Laurent-Maquin, P Laquerrière - Acta biomaterialia, 2011 - Elsevier
Calcium phosphates are widely used as biomaterials and strontium (Sr) is known to have
the ability to modify the bone balance towards osteosynthesis. In the present study we …

Inflammatory cell response to calcium phosphate biomaterial particles: an overview

F Velard, J Braux, J Amedee, P Laquerriere - Acta biomaterialia, 2013 - Elsevier
Bone is a metabolically active and highly organized tissue consisting of a mineral phase of
hydroxyapatite (HA) and amorphous calcium phosphate (CaP) crystals deposited in an …

Multilineage differentiation of human mesenchymal stem cells in a three-dimensional nanofibrous scaffold

WJ Li, R Tuli, X Huang, P Laquerriere, RS Tuan - Biomaterials, 2005 - Elsevier
Functional engineering of musculoskeletal tissues generally involves the use of differentiated
or progenitor cells seeded with specific growth factors in biomaterial scaffolds. Ideally, the …

Structural characterization of sol–gel derived Sr-substituted calcium phosphates with anti-osteoporotic and anti-inflammatory properties

G Renaudin, P Laquerriere, Y Filinchuk… - Journal of Materials …, 2008 - pubs.rsc.org
Sol–gel chemistry has been successfully used to prepare un-doped and Sr-doped calcium
phosphate ceramics exhibiting a porous structure. The samples composition is very close to …

Biological relevance of RGD‐integrin subtype‐specific ligands in cancer

…, Q Fuchs, M Pierrevelcin, P Laquerriere… - …, 2021 - Wiley Online Library
Integrins are heterodimeric transmembrane proteins able to connect cells with the micro‐environment.
They represent a family of receptors involved in almost all the hallmarks of cancer. …

Importance of hydroxyapatite particles characteristics on cytokines production by human monocytes in vitro

P Laquerriere, A Grandjean-Laquerriere, E Jallot… - Biomaterials, 2003 - Elsevier
Calcium phosphate bioceramics have been applied as bone substitutes for several decades.
Aseptic loosening after total joint arthroplasty is a major problem in orthopaedic surgery. …

[HTML][HTML] Transmembrane domain targeting peptide antagonizing ErbB2/Neu inhibits breast tumor growth and metastasis

…, P Hubert, G Cremel, G Orend, P Laquerriere… - Cell reports, 2014 - cell.com
Breast cancer is still a deadly disease despite major achievements in targeted therapies
designed to block ligands or ligand-binding subunits of major tyrosine kinase receptors. …

A clinical assessment of the Mucus Shaver: a device to keep the endotracheal tube free from secretions

…, EA Bittner, T Kolobow, P Laquerriere… - Critical care …, 2012 - journals.lww.com
Objective: We evaluated a new device designed to clean the endotracheal tube in mechanically
ventilated patients, the Mucus Shaver. Design: Prospective, randomized trial. Setting: …

Influence of the zinc concentration of sol–gel derived zinc substituted hydroxyapatite on cytokine production by human monocytes in vitro

A Grandjean-Laquerriere, P Laquerriere, E Jallot… - Biomaterials, 2006 - Elsevier
A possible complication associated with the implantation of hydroxyapatite (HA)-based
prosthesis is the release of particles. These particles can be phagocyted by monocytes that are …

Involvement of toll-like receptor 4 in the inflammatory reaction induced by hydroxyapatite particles

A Grandjean-Laquerriere, O Tabary, J Jacquot… - Biomaterials, 2007 - Elsevier
Hydroxyapatite (HA) is widely used to coat metal parts in order to improve their biocompatibility.
Analysis of retrieved tissues associated with failed implants, suggest that phagocytosis …