Background: BRCA1 and BRCA2 mutations in general populations and in various types of
cancers have not been well characterized. We investigated the presence of these mutations …

Prediction of clinical outcome in cancer is usually achieved by histopathological evaluation
of tissue samples obtained during surgical resection of the primary tumor. Traditional tumor …

BACKGROUND: The heritable fraction of ovarian cancer exceeds that of any other common
adult cancer. Most inherited cases of ovarian cancer are due to a germline mutation in …

The theory of Lexical Phonology, which forms one of the themes of this volume, was developed
by Paul Kiparsky and KP Mohanan and first introduced in monographs appearing in the …

The cancer stem cell (CSC) model proposes that tumors have a hierarchical organization in
which only some cells indefinitely self-renew and thereby sustain tumor growth. In addition, …

Occult invasive and intraepithelial carcinomas have been identified in the tubal fimbria of
BRCA mutation carriers undergoing prophylactic surgery, and recently described lesions …

Publisher Summary This chapter reviews the special status of coronal harmony in the
consonant harmony systems. It focuses on several asymmetric properties of consonant harmony …

Many high-grade serous carcinomas (HGSCs) of the pelvis are thought to originate in the
distal portion of the fallopian tube. Serous tubal intra-epithelial carcinoma (STIC) lesions are …

Purpose: To identify molecular alterations potentially involved in predisposition to adnexal
serous carcinoma (SerCa) in the nonmalignant fallopian tube epithelium (FTE) of BRCA1/2 …

Background Studies have suggested that the 5-year survival of women with ovarian cancer
and a BRCA1 or BRCA2 mutation is better than expected. We sought to evaluate the impact …