Zika virus (ZIKV) infection in utero might lead to microcephaly and other congenital defects.
Since no specific therapy is available thus far, there is an urgent need for the discovery of …

Since the emergence of Zika virus (ZIKV), reports of microcephaly have increased considerably
in Brazil; however, causality between the viral epidemic and malformations in fetal brains …

Zika virus (ZIKV) has been associated with microcephaly and other brain abnormalities;
however, the molecular consequences of ZIKV to human brain development are still not fully …

The proneural factor Ascl1 controls multiple steps of neurogenesis in the embryonic brain,
including progenitor division and neuronal migration. Here we show that Cenpj, also known …

The northeast (NE) region of Brazil commonly goes through drought periods, which favor
cyanobacterial blooms, capable of producing neurotoxins with implications for human and …

Five years after the identification of Zika virus as a human teratogen, we reviewed the early
clinical manifestations, collectively called congenital Zika syndrome (CZS). Children with …

Advances in translational neuroscience require experimental models recapitulating the
complexity of the human brain. In contrast to conventional 2D cell culture models and animal …

The Zika virus (ZIKV) is a mosquito-borne Flavivirus and can be transmitted through an
infected mosquito bite or through human-to-human interaction by sexual activity, blood …

Neuronal migration is a fundamental process of brain development, and its disruption underlies
devastating neurodevelopmental disorders. The transcriptional programs governing this …

Purpose Our main goal is to identify the alterations in the amniotic fluid (AF) metabolome in
Zika virus (ZIKV)‐infected patients and their relation to congenital Zika syndrome (CZS) …