User profiles for Patrick Chen

Patrick Chen

- Verified email at ucla.edu - Cited by 708

Patrick M. Chen

- Verified email at mgh.harvard.edu - Cited by 531

Patrick H Chen

- Verified email at binghamton.edu - Cited by 455

Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35

…, M Hackett, M Hugunin, S Seshagiri, K Brady, P Chen… - Science, 1995 - science.org
The baculovirus antiapoptotic protein p35 inhibited the proteolytic activity of human interleukin-1β
converting enzyme (ICE) and three of its homologs in enzymatic assays. Coexpression …

[HTML][HTML] Aspergillus fumigatus Triggers Inflammatory Responses by Stage-Specific β-Glucan Display

…, HL Van Epps, A Rivera, LA Morgan, PL Chen… - PLoS …, 2005 - journals.plos.org
Inhalation of fungal spores (conidia) occurs commonly and, in specific circumstances, can
result in invasive disease. We investigated the murine inflammatory response to conidia of …

RNA mango aptamer-fluorophore: a bright, high-affinity complex for RNA labeling and tracking

…, R Cojocaru, PSK Chen… - ACS chemical …, 2014 - ACS Publications
Because RNA lacks strong intrinsic fluorescence, it has proven challenging to track RNA
molecules in real time. To address this problem and to allow the purification of fluorescently …

[PDF][PDF] Neural circuit mechanisms of social behavior

P Chen, W Hong - Neuron, 2018 - cell.com
We live in a world that is largely socially constructed, and we are constantly involved in and
fundamentally influenced by a broad array of complex social interactions. Social behaviors …

Segmentation by texture using a co-occurrence matrix and a split-and-merge algorithm

PC Chen, T Pavlidis - Computer graphics and image processing, 1979 - Elsevier
The co-occurrence matrix is used for segmentation according to texture. It is first evaluated
on a set of regions forming two levels of the quadratic picture tree (or pyramid). If the matrices …

Morphological and positional asymmetries of young children with functional unilateral posterior crossbite

…, PH Buschang, GS Throckmorton, P Chen - American Journal of …, 2001 - Elsevier
This prospective clinical study evaluated the morphological and positional mandibular
asymmetry of young patients with functional unilateral posterior crossbite. The sample included 9 …

miRNA Profiling for Diagnosis and Prognosis of Human Cancer

C Jay, J Nemunaitis, P Chen, P Fulgham… - DNA and cell …, 2007 - liebertpub.com
MicroRNAs (miRNAs) are a recently discovered class of small (∼18–24 nt) nucleic acids
that negatively regulate gene expression. This novel class of molecules modulates a wide …

Sign-opt: A query-efficient hard-label adversarial attack

M Cheng, S Singh, P Chen, PY Chen, S Liu… - arXiv preprint arXiv …, 2019 - arxiv.org
We study the most practical problem setup for evaluating adversarial robustness of a machine
learning system with limited access: the hard-label black-box attack setting for generating …

Association of traumatic brain injury with the risk of developing chronic cardiovascular, endocrine, neurological, and psychiatric disorders

S Izzy, PM Chen, Z Tahir, R Grashow… - JAMA network …, 2022 - jamanetwork.com
Importance Increased risk of neurological and psychiatric conditions after traumatic brain injury
(TBI) is well-defined. However, cardiovascular and endocrine comorbidity risk after TBI in …

[PDF][PDF] Sexually dimorphic control of parenting behavior by the medial amygdala

PB Chen, RK Hu, YE Wu, L Pan, S Huang… - Cell, 2019 - cell.com
Social behaviors, including behaviors directed toward young offspring, exhibit striking sex
differences. Understanding how these sexually dimorphic behaviors are regulated at the level …