[HTML][HTML] Localization and abundance analysis of human lncRNAs at single-cell and single-molecule resolution

MN Cabili, MC Dunagin, PD McClanahan, A Biaesch… - Genome biology, 2015 - Springer
Background Long non-coding RNAs (lncRNAs) have been implicated in diverse biological
processes. In contrast to extensive genomic annotation of lncRNA transcripts, far fewer have …

Self-assembly of carboranethiol isomers on Au {111}: intermolecular interactions determined by molecular dipole orientations

…, P Han, M Kim, AR Kurland, PD McClanahan… - ACS …, 2009 - ACS Publications
Self-assembled monolayer (SAM) structures and properties are dominated by two
interactions: those between the substrate and adsorbate and those between the adsorbates …

Developmental emergence of sleep rhythms enables long-term memory in Drosophila

AR Poe, L Zhu, M Szuperak, PD McClanahan… - Science …, 2023 - science.org
In adulthood, sleep-wake rhythms are one of the most prominent behaviors under circadian
control. However, during early life, sleep is spread across the 24-hour day. The mechanism …

[HTML][HTML] Single-cell differences in matrix gene expression do not predict matrix deposition

…, CM McLeod, MJ Farrell, PD McClanahan… - Nature …, 2016 - nature.com
Mesenchymal stem cells (MSCs) display substantial cell-to-cell heterogeneity, complicating
their use in regenerative medicine. However, conventional bulk assays mask this variability. …

Comparing Caenorhabditis elegans gentle and harsh touch response behavior using a multiplexed hydraulic microfluidic device

PD McClanahan, JH Xu, C Fang-Yen - Integrative biology, 2017 - academic.oup.com
The roundworm Caenorhabditis elegans is an important model system for understanding
the genetics and physiology of touch. Classical assays for C. elegans touch, which involve …

Simple, robust molecular self-assembly on germanium

…, HR Bednar, JA Lawrence, PD McClanahan… - Chemical …, 2011 - pubs.rsc.org
We report the facile fabrication of high-quality, robust alkanethiolate self-assembled monolayers
(SAMs) on germanium substrates. Our approach to produce SAMs on technologically …

[PDF][PDF] Sleep induction by mechanosensory stimulation in Drosophila

A Öztürk-Çolak, S Inami, JR Buchler, PD McClanahan… - Cell reports, 2020 - cell.com
People tend to fall asleep when gently rocked or vibrated. Experimental studies have shown
that rocking promotes sleep in humans and mice. However, the mechanisms underlying the …

[HTML][HTML] Automated scoring of nematode nictation on a textured background

PD McClanahan, L Golinelli, TA Le, L Temmerman - Plos One, 2023 - journals.plos.org
Entomopathogenic nematodes, including Steinernema spp., play an increasingly important
role as biological alternatives to chemical pesticides. The infective juveniles of these worms …

Dehydrated Caenorhabditis elegans Stocks Are Resistant to Multiple Freeze-Thaw Cycles

PD McClanahan, RJ McCloskey… - G3: Genes …, 2020 - academic.oup.com
Ultracold preservation is widely used for storage of genetic stocks of Caenorhabditis elegans.
Current cryopreservation protocols are vulnerable to refrigeration failures, which can result …

[HTML][HTML] A quiescent state following mild sensory arousal in Caenorhabditis elegans is potentiated by stress

PD McClanahan, JM Dubuque… - Scientific Reports, 2020 - nature.com
An animal’s behavioral and physiological response to stressors includes changes to its
responses to stimuli. How such changes occur is not well understood. Here we describe a …