The B73 maize genome: complexity, diversity, and dynamics
We report an improved draft nucleotide sequence of the 2.3-gigabase genome of maize, an
important crop plant and model for biological research. Over 32,000 genes were predicted, …
important crop plant and model for biological research. Over 32,000 genes were predicted, …
[HTML][HTML] The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes
H Skaletsky, T Kuroda-Kawaguchi, PJ Minx… - Nature, 2003 - nature.com
The male-specific region of the Y chromosome, the MSY, differentiates the sexes and
comprises 95% of the chromosome's length. Here, we report that the MSY is a mosaic of …
comprises 95% of the chromosome's length. Here, we report that the MSY is a mosaic of …
[HTML][HTML] Evolution of genes and genomes on the Drosophila phylogeny
…, B McKernan, K McKernan, M Mendez-Lago, P Minx… - Nature, 2007 - hal.science
Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves
the precision and sensitivity of evolutionary inference, producing more robust results than …
the precision and sensitivity of evolutionary inference, producing more robust results than …
[HTML][HTML] DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome
…, J Conyers, N Sander, X Shi, JR Osborne, P Minx… - Nature, 2008 - nature.com
Acute myeloid leukaemia is a highly malignant haematopoietic tumour that affects about
13,000 adults in the United States each year. The treatment of this disease has changed little in …
13,000 adults in the United States each year. The treatment of this disease has changed little in …
Evolutionary and biomedical insights from the rhesus macaque genome
The rhesus macaque (Macaca mulatta) is an abundant primate species that diverged from
the ancestors of Homo sapiens about 25 million years ago. Because they are genetically and …
the ancestors of Homo sapiens about 25 million years ago. Because they are genetically and …
[HTML][HTML] The Genome Sequence of Caenorhabditis briggsae: A Platform for Comparative Genomics
The soil nematodes Caenorhabditis briggsae and Caenorhabditis elegans diverged from a
common ancestor roughly 100 million years ago and yet are almost indistinguishable by eye. …
common ancestor roughly 100 million years ago and yet are almost indistinguishable by eye. …
The AZFc region of the Y chromosome features massive palindromes and uniform recurrent deletions in infertile men
…, H Skaletsky, LG Brown, PJ Minx… - Nature …, 2001 - nature.com
Deletions of the AZFc (azoospermia factor c) region of the Y chromosome are the most
common known cause of spermatogenic failure. We determined the complete nucleotide …
common known cause of spermatogenic failure. We determined the complete nucleotide …
Abundant gene conversion between arms of palindromes in human and ape Y chromosomes
S Rozen, H Skaletsky, JD Marszalek, PJ Minx… - Nature, 2003 - nature.com
Eight palindromes comprise one-quarter of the euchromatic DNA of the male-specific region
of the human Y chromosome, the MSY 1 . They contain many testis-specific genes and …
of the human Y chromosome, the MSY 1 . They contain many testis-specific genes and …
[HTML][HTML] Elephant shark genome provides unique insights into gnathostome evolution
The emergence of jawed vertebrates (gnathostomes) from jawless vertebrates was accompanied
by major morphological and physiological innovations, such as hinged jaws, paired …
by major morphological and physiological innovations, such as hinged jaws, paired …
[HTML][HTML] Evolution of symbiotic bacteria in the distal human intestine
The adult human intestine contains trillions of bacteria, representing hundreds of species
and thousands of subspecies. Little is known about the selective pressures that have shaped …
and thousands of subspecies. Little is known about the selective pressures that have shaped …