The B73 maize genome: complexity, diversity, and dynamics

…, C Liang, J Zhang, L Fulton, TA Graves, P Minx… - science, 2009 - science.org
We report an improved draft nucleotide sequence of the 2.3-gigabase genome of maize, an
important crop plant and model for biological research. Over 32,000 genes were predicted, …

[HTML][HTML] The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes

H Skaletsky, T Kuroda-Kawaguchi, PJ Minx… - Nature, 2003 - nature.com
The male-specific region of the Y chromosome, the MSY, differentiates the sexes and
comprises 95% of the chromosome's length. Here, we report that the MSY is a mosaic of …

[HTML][HTML] Evolution of genes and genomes on the Drosophila phylogeny

…, B McKernan, K McKernan, M Mendez-Lago, P Minx… - Nature, 2007 - hal.science
Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves
the precision and sensitivity of evolutionary inference, producing more robust results than …

[HTML][HTML] DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome

…, J Conyers, N Sander, X Shi, JR Osborne, P Minx… - Nature, 2008 - nature.com
Acute myeloid leukaemia is a highly malignant haematopoietic tumour that affects about
13,000 adults in the United States each year. The treatment of this disease has changed little in …

Evolutionary and biomedical insights from the rhesus macaque genome

…, Y Feng, AL Halpern, LDW Hillier, X Huang, P Minx… - science, 2007 - science.org
The rhesus macaque (Macaca mulatta) is an abundant primate species that diverged from
the ancestors of Homo sapiens about 25 million years ago. Because they are genetically and …

[HTML][HTML] The Genome Sequence of Caenorhabditis briggsae: A Platform for Comparative Genomics

…, ER Mardis, MA Marra, TL Miner, P Minx… - PLoS …, 2003 - journals.plos.org
The soil nematodes Caenorhabditis briggsae and Caenorhabditis elegans diverged from a
common ancestor roughly 100 million years ago and yet are almost indistinguishable by eye. …

The AZFc region of the Y chromosome features massive palindromes and uniform recurrent deletions in infertile men

…, H Skaletsky, LG Brown, PJ Minx… - Nature …, 2001 - nature.com
Deletions of the AZFc (azoospermia factor c) region of the Y chromosome are the most
common known cause of spermatogenic failure. We determined the complete nucleotide …

Abundant gene conversion between arms of palindromes in human and ape Y chromosomes

S Rozen, H Skaletsky, JD Marszalek, PJ Minx… - Nature, 2003 - nature.com
Eight palindromes comprise one-quarter of the euchromatic DNA of the male-specific region
of the human Y chromosome, the MSY 1 . They contain many testis-specific genes and …

[HTML][HTML] Elephant shark genome provides unique insights into gnathostome evolution

…, BJ Raney, PW Ingham, A Tay, LDW Hillier, P Minx… - Nature, 2014 - nature.com
The emergence of jawed vertebrates (gnathostomes) from jawless vertebrates was accompanied
by major morphological and physiological innovations, such as hinged jaws, paired …

[HTML][HTML] Evolution of symbiotic bacteria in the distal human intestine

…, EC Martens, B Henrissat, PM Coutinho, P Minx… - PLoS …, 2007 - journals.plos.org
The adult human intestine contains trillions of bacteria, representing hundreds of species
and thousands of subspecies. Little is known about the selective pressures that have shaped …