Cadherins constitute a superfamily of cell adhesion molecules involved in cell‐cell interaction,
histogenesis and cellular transformation. They have been implicated in the development …

The neural crest is induced at the edge between the neural plate and the nonneural ectoderm,
in an area called the neural (plate) border, during gastrulation and neurulation. In recent …

Huntington's disease (HD) is a neurodegenerative disorder that is best known for its effect
on motor control. Mood disturbances such as depression, anxiety, and irritability also have a …

Huntingtin (HTT), the protein mutated in Huntington's disease (HD), controls transport of the
neurotrophin, brain-derived neurotrophic factor (BDNF), within corticostriatal neurons. …

Insm1 (IA-1) encodes a Zn-finger factor that is expressed in the developing nervous system.
We demonstrate here that the development of the sympatho-adrenal lineage is severely …

Endothelin receptors (Ednr) are members of the family of G protein-coupled receptors (GPCR)
with seven transmembrane domains. Their ligands, endothelins (Edn), constitute a family …

When a neurotrophin binds at the presynapse, it sends survival signals all the way to the
nucleus on signaling endosomes. These endosomes fuel their own journey with on-board …

In many regions of the developing CNS, distinct cell types are born at different times. The
means by which discrete and stereotyped temporal switches in cellular identities are acquired …

Huntington's disease (HD) is a devastating genetic neurodegenerative disorder. Major
depressive disorder and more generally mood disorders are a major component of the symptoms …

Endothelin receptors B (Ednrb) are involved in the development of the enteric and melanocytic
lineages, which originate from neural crest cells (NCCs). In mice, trunk NCCs and their …