User profiles for Patrick R. Lennard
Patrick R. LennardPhD Candidate | University of Edinburgh and Leiden University Verified email at ed.ac.uk Cited by 51 |
[HTML][HTML] Synergism between the synthetic antibacterial and antibiofilm peptide (SAAP)-148 and halicin
ME van Gent, TJK van der Reijden, PR Lennard… - Antibiotics, 2022 - mdpi.com
Recently, using a deep learning approach, the novel antibiotic halicin was discovered. We
compared the antibacterial activities of two novel bactericidal antimicrobial agents, ie, the …
compared the antibacterial activities of two novel bactericidal antimicrobial agents, ie, the …
A novel system to map protein interactions reveals evolutionarily conserved immune evasion pathways on transmissible cancers
Around 40% of humans and Tasmanian devils (Sarcophilus harrisii) develop cancer in their
lifetime, compared to less than 10% for most species. In addition, devils are affected by two …
lifetime, compared to less than 10% for most species. In addition, devils are affected by two …
[HTML][HTML] Complementary Activities of Host Defence Peptides and Antibiotics in Combating Antimicrobial Resistant Bacteria
PR Lennard, PS Hiemstra, PH Nibbering - Antibiotics, 2023 - mdpi.com
Due to their ability to eliminate antimicrobial resistant (AMR) bacteria and to modulate the
immune response, host defence peptides (HDPs) hold great promise for the clinical treatment …
immune response, host defence peptides (HDPs) hold great promise for the clinical treatment …
Tasmanian devil CD28 and CTLA4 capture CD80 and CD86 from adjacent cells
Immune checkpoint immunotherapy is a pillar of human oncology treatment with potential
for non-human species. The first checkpoint immunotherapy approved for human cancers …
for non-human species. The first checkpoint immunotherapy approved for human cancers …
Generation and testing of fluorescent adaptable simple theranostic (FAST) proteins
This protocol provides a step-by-step method to create recombinant fluorescent fusion proteins
that can be secreted from mammalian cell lines. This builds on many other recombinant …
that can be secreted from mammalian cell lines. This builds on many other recombinant …
Evaluation of a global training program in One Health communication
DJ Thomson, D Ma, PR Lennard… - One Health & …, 2023 - research.ed.ac.uk
Aim: A global Train-the-Trainer Program, focused on improving the communication techniques
of One Health advocates, is assessed and evaluated in this study. Methods: Between …
of One Health advocates, is assessed and evaluated in this study. Methods: Between …
Immune checkpoint proteins are conserved across 160 million years of evolution and are expressed on transmissible cancers
Around 40% of humans and captive Tasmanian devils (Sarcophilus harrisii) develop cancer,
compared to less than 10% for most species. Tasmanian devils also suffer from two of the …
compared to less than 10% for most species. Tasmanian devils also suffer from two of the …
Third‐order rate constants of atmospheric importance
R Patrick, DM Golden - International journal of chemical …, 1983 - Wiley Online Library
… where ZU is the Lennard-Jones collision frequency, and f(E,J) is the distribution'of molecules
among the available rovibrational states. Troe's [4,5] formalism starts from eq. (1) and by a …
among the available rovibrational states. Troe's [4,5] formalism starts from eq. (1) and by a …
Computational study of the hydroperoxo+ hydroperoxo and hydroperoxo-d+ hydroperoxo-d reactions
R Patrick, JR Barker, DM Golden - The Journal of Physical …, 1984 - ACS Publications
… j is the barrier to redissociation, kf is the high-pressure limiting rate constant for reaction 1,
Z is the Lennard-Jones collision frequency, ß is the collisional deactivation efficiency, and f(E) …
Z is the Lennard-Jones collision frequency, ß is the collisional deactivation efficiency, and f(E) …
A high pressure rate constant for CH 3+ H and an analysis of the kinetics of the CH 3+ H→ CH 4 reaction
R Patrick, MJ Pilling, GJ Rogers - Chemical Physics, 1980 - Elsevier
… Following Troe [40] Z was equated to the LennardJones collision frequency defmed by …
where NIL is the Avogadro number, p*_hl: the reduced molar mass and oA_nr the Lennard-Jones …
where NIL is the Avogadro number, p*_hl: the reduced molar mass and oA_nr the Lennard-Jones …