It is now widely recognized that neutrophils are highly versatile and sophisticated cells that
display de novo synthetic capacity and may greatly extend their lifespan. In addition, …

New evidence has challenged the outdated dogma that neutrophils are a homogeneous
population of short-lived cells. Although neutrophil subpopulations with distinct functions have …

Recent findings have uncovered novel fascinating aspects of the biology of neutrophils, which
ultimately attribute to these cells a broader role in inflammation and immunity. One aspect …

B lymphocyte stimulator (BLyS) is a novel member of the TNF ligand superfamily that is
important in B cell maturation and survival. We demonstrate that human neutrophils, after …

The identification of discrete neutrophil populations, as well as the characterization of their
immunoregulatory properties, is an emerging topic under extensive investigation. In such …

Traditionally viewed as poorly plastic, neutrophils are now recognized as functionally
diverse; however, the extent and determinants of neutrophil heterogeneity in humans remain …

The angiogenic activity of CXC-ELR+ chemokines, including CXCL8/IL-8, CXCL1/macrophage
inflammatory protein-2 (MIP-2), and CXCL1/growth-related oncogene-α in the Matrigel …

A20 is a ubiquitin modifying enzyme that restricts NF-κB signals and protects cells against
tumor necrosis factor (TNF)-induced programmed cell death. Given recent data linking A20 (…

We have recently shown that, in human neutrophils, interleukin-10 (IL-10) fails to induce
specific DNA-binding activities to the gamma-interferon response region (GRR), a regulatory …

The inflammatory and IFN pathways of innate immunity play a key role in the resistance and
pathogenesis of coronavirus disease 2019 (COVID-19). Innate sensors and SARS-CoV-2–…