Activation priming and cytokine polyfunctionality modulate the enhanced functionality of low-affinity CD19 CAR T cells

…, J Sufi, P Puigdevall Costa… - Blood …, 2023 - ashpublications.org
We recently described a low-affinity second-generation CD19 chimeric antigen receptor (CAR)
CAT that showed enhanced expansion, cytotoxicity, and antitumor efficacy compared …

Characterization of cortical neurodevelopment in vitro using gene expression and morphology profiles from single cells

…, Z Yang, R Woldegebriel, A Ganna, PP Costa… - bioRxiv, 2023 - biorxiv.org
Differentiation of induced pluripotent stem cells (iPSC) towards different neuronal lineages
has enabled diverse cellular models of human neurodevelopment and related disorders. …

Identification of genetic modifiers of penetrance in human inherited disease

P Puigdevall Costa - 2019 - tdx.cat
Understanding the molecular basis of human inherited disease is a challenging task due to
the complexity of mapping the genotype to the phenotype. The study of diseases running in …

[PDF][PDF] Activation priming and cytokine polyfunctionality modulate the enhanced functionality of low-affinity CD19 CAR T cells

LCAT CAR - 2023 - pdfs.semanticscholar.org
T cells that are genetically engineered to express CD19 chimeric antigen receptors (CAR T
cells) have shown remarkable efficacy in relapsed/refractory (r/r) B-cell malignancies, …

High-throughput molecular profiling of the fetal inflammatory response in extremely low gestational age newborns

D Costa Coto - 2019 - tdx.cat
… I very much appreciate Pau Puigdevall for his assistance in writing the thesis and for accepting
to participate in our pilot RNA sequencing experiment of dried blood spots. Many thanks …

[HTML][HTML] Internal fixation of osteochondritis dissecans of the knee leads to good long-term outcomes and high degree of healing without differences between fixation …

S Perelli, AR Molina Romoli, M Costa-Paz… - Journal of clinical …, 2019 - mdpi.com
The aim of the present study is to describe results at long-term follow-up of internal fixation of
unstable Osteochondritis Dissecans (OCD) achieved with three different fixation devices in …

Amplification of human interneuron progenitors promotes brain tumors and neurological defects

OL Eichmüller, NS Corsini, Á Vértesy, I Morassut… - Science, 2022 - science.org
Evolutionary development of the human brain is characterized by the expansion of various
brain regions. Here, we show that developmental processes specific to humans are …

The institution of linguistic dissidence in the Balearic Islands: Ideological dynamics of Catalan standardisation

LJ Duane Bernedo - 2018 - openaccess.uoc.edu
This thesis comprises an ethnographic description of the recent development of linguistic
dissidence on the Balearic Islands: the establishment of a belief within the archipelago's socio-…

Cosmopolitan Taste: The Morphing of the New Catalan Cuisine

A Pujol - Food, Culture & Society, 2009 - Taylor & Francis
… Bulli opens in a hidden caleta in the Costa Brava. The resulting synesthetic finish arouses
… ’s revision of the classic trinxat; or Fina Puigdevall’s minimalist approach to patates amb suc …

From the UOC on the internet to the network-UOC: annual report on the Universitat Oberta de Catalunya: academic year 2007-2008

M Boixadera-Ibern, I Solà Albareda, M Taulats Pahissa… - 2009 - openaccess.uoc.edu
As we reach fifteen years of activity, the UOC is to enter a decisive stage in consolidating its
position in the Catalan, Ibero-American and European university systems. It will be a year of …