User profiles for Paul A. MacAry
Paul MacAryNational University of Singapore Verified email at nus.edu.sg Cited by 12597 |
[HTML][HTML] The trinity of COVID-19: immunity, inflammation and intervention
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the ongoing coronavirus disease 2019 (COVID-19) pandemic. Alongside investigations into …
the ongoing coronavirus disease 2019 (COVID-19) pandemic. Alongside investigations into …
Current Views on the Clinical Relevance of Blastocystis spp.
Blastocystis is an enteric protistan parasite of uncertain clinical relevance. Recent studies
indicate that the parasite is a species complex and humans are potentially hosts to nine …
indicate that the parasite is a species complex and humans are potentially hosts to nine …
Structure and function: heat shock proteins and adaptive immunity
Heat shock proteins (HSPs) have been implicated in the stimulation and generation of both
innate and adaptive immunity. The ability of HSPs to bind antigenic peptides and deliver …
innate and adaptive immunity. The ability of HSPs to bind antigenic peptides and deliver …
Loss of function of a lupus-associated FcγRIIb polymorphism through exclusion from lipid rafts
Dysfunction of receptors for IgG (FcγRs) has been thought to be involved in the pathogenesis
of systemic lupus erythematosus (SLE). We show that a recently described SLE-associated …
of systemic lupus erythematosus (SLE). We show that a recently described SLE-associated …
A CD8+ T cell transcription signature predicts prognosis in autoimmune disease
Autoimmune diseases are common and debilitating, but their severe manifestations could
be reduced if biomarkers were available to allow individual tailoring of potentially toxic …
be reduced if biomarkers were available to allow individual tailoring of potentially toxic …
Lung CD103+ dendritic cells efficiently transport influenza virus to the lymph node and load viral antigen onto MHC class I for presentation to CD8 T cells
…, FC Lew, KL Wong, BJ Hanson, PA Macary… - The Journal of …, 2011 - journals.aai.org
The uptake, transport, and presentation of Ags by lung dendritic cells (DCs) are central to
the initiation of CD8 T cell responses against respiratory viruses. Although several studies …
the initiation of CD8 T cell responses against respiratory viruses. Although several studies …
The structural basis for serotype-specific neutralization of dengue virus by a human antibody
Dengue virus (DENV) is a mosquito-borne flavivirus that affects 2.5 billion people worldwide.
There are four dengue serotypes (DENV1 to DENV4), and infection with one elicits lifelong …
There are four dengue serotypes (DENV1 to DENV4), and infection with one elicits lifelong …
Differential Targeting of Viral Components by CD4+ versus CD8+ T Lymphocytes in Dengue Virus Infection
Dengue virus (DENV) is the principal arthropod-borne viral pathogen afflicting human
populations. While repertoires of antibodies to DENV have been linked to protection or enhanced …
populations. While repertoires of antibodies to DENV have been linked to protection or enhanced …
Dendritic cell stimulation by mycobacterial Hsp70 is mediated through CCR5
An effective host immune response to mycobacterial infection must control pathogen
dissemination without inducing immunopathology. Constitutive overexpression of mycobacterial …
dissemination without inducing immunopathology. Constitutive overexpression of mycobacterial …
[HTML][HTML] Lower vaccine-acquired immunity in the elderly population following two-dose BNT162b2 vaccination is alleviated by a third vaccine dose
Understanding the impact of age on vaccinations is essential for the design and delivery of
vaccines against SARS-CoV-2. Here, we present findings from a comprehensive analysis of …
vaccines against SARS-CoV-2. Here, we present findings from a comprehensive analysis of …