User profiles for Paul A. MacAry

Paul MacAry

National University of Singapore
Verified email at nus.edu.sg
Cited by 12597

[HTML][HTML] The trinity of COVID-19: immunity, inflammation and intervention

MZ Tay, CM Poh, L Rénia, PA MacAry… - Nature Reviews …, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the ongoing coronavirus disease 2019 (COVID-19) pandemic. Alongside investigations into …

Current Views on the Clinical Relevance of Blastocystis spp.

…, H Mirza, JDW Teo, B Wu, PA MacAry - Current infectious disease …, 2010 - Springer
Blastocystis is an enteric protistan parasite of uncertain clinical relevance. Recent studies
indicate that the parasite is a species complex and humans are potentially hosts to nine …

Structure and function: heat shock proteins and adaptive immunity

B Javid, PA MacAry, PJ Lehner - The Journal of Immunology, 2007 - journals.aai.org
Heat shock proteins (HSPs) have been implicated in the stimulation and generation of both
innate and adaptive immunity. The ability of HSPs to bind antigenic peptides and deliver …

Loss of function of a lupus-associated FcγRIIb polymorphism through exclusion from lipid rafts

…, KR Heilbronn, DR Rosner, PA MacAry… - Nature medicine, 2005 - nature.com
Dysfunction of receptors for IgG (FcγRs) has been thought to be involved in the pathogenesis
of systemic lupus erythematosus (SLE). We show that a recently described SLE-associated …

A CD8+ T cell transcription signature predicts prognosis in autoimmune disease

…, V Jovanovic, DM Kemeny, AJ Pollard, PA MacAry… - Nature medicine, 2010 - nature.com
Autoimmune diseases are common and debilitating, but their severe manifestations could
be reduced if biomarkers were available to allow individual tailoring of potentially toxic …

Lung CD103+ dendritic cells efficiently transport influenza virus to the lymph node and load viral antigen onto MHC class I for presentation to CD8 T cells

…, FC Lew, KL Wong, BJ Hanson, PA Macary… - The Journal of …, 2011 - journals.aai.org
The uptake, transport, and presentation of Ags by lung dendritic cells (DCs) are central to
the initiation of CD8 T cell responses against respiratory viruses. Although several studies …

The structural basis for serotype-specific neutralization of dengue virus by a human antibody

…, PY Shi, BJ Hanson, SM Lok, PA MacAry - Science translational …, 2012 - science.org
Dengue virus (DENV) is a mosquito-borne flavivirus that affects 2.5 billion people worldwide.
There are four dengue serotypes (DENV1 to DENV4), and infection with one elicits lifelong …

Differential Targeting of Viral Components by CD4+ versus CD8+ T Lymphocytes in Dengue Virus Infection

…, A Bertoletti, DM Kemeny, PA MacAry - Journal of …, 2013 - Am Soc Microbiol
Dengue virus (DENV) is the principal arthropod-borne viral pathogen afflicting human
populations. While repertoires of antibodies to DENV have been linked to protection or enhanced …

Dendritic cell stimulation by mycobacterial Hsp70 is mediated through CCR5

RA Floto, PA MacAry, JM Boname, TS Mien… - Science, 2006 - science.org
An effective host immune response to mycobacterial infection must control pathogen
dissemination without inducing immunopathology. Constitutive overexpression of mycobacterial …

[HTML][HTML] Lower vaccine-acquired immunity in the elderly population following two-dose BNT162b2 vaccination is alleviated by a third vaccine dose

…, YS Leo, PA MacAry… - Nature …, 2022 - nature.com
Understanding the impact of age on vaccinations is essential for the design and delivery of
vaccines against SARS-CoV-2. Here, we present findings from a comprehensive analysis of …