The development of snake antivenoms more than a century ago should have heralded
effective treatment of the scourge of snakebite envenoming in impoverished, mostly rural …

Most temperate phages encode an integrase for integration and excision of the prophage.
Integrases belong either to the λ Int family of tyrosine recombinases or to a subgroup of the …

Neuroinflammation plays a central role in the neuropathogenesis of a wide-spectrum of
neurologic and psychiatric disease, but current neuroimaging methods to detect and …

Bitis arietans is considered one of the most medically significant snakes in Africa, primarily
due to a combination of its extensive geographical distribution, common occurrence and …

In eukaryotes, the degradation of cellular mRNAs is accomplished by Xrn1 and the cytoplasmic
exosome. Because viral RNAs often lack canonical caps or poly-A tails, they can also be …

Venom is a critical evolutionary innovation enabling venomous snakes to become successful
limbless predators; it is therefore vital that venomous snakes possess a highly efficient …

Although diagnosing the syndrome of dementia is largely a clinical endeavor, neuroimaging
plays an increasingly important role in accurately determining the underlying etiology, …

Tyrosine family site‐specific recombinases (YRs), named after the active site tyrosine nucleophile
they utilize for DNA strand breakage, are widely distributed among prokaryotes. They …

Evolutionary analyses have revealed that most host-encoded restriction factors against HIV
have experienced virus-driven selection during primate evolution. However, HIV also …

Viruses are a major focus of current research efforts because of their detrimental impact on
humanity and their ubiquity within the environment. Bacteriophages have long been used to …