User profiles for Paul A. Scheet
Paul ScheetUniversity of Texas MD Anderson Cancer Center Verified email at mdanderson.org Cited by 43832 |
Newly identified loci that influence lipid concentrations and risk of coronary artery disease
To identify genetic variants influencing plasma lipid concentrations, we first used genotype
imputation and meta-analysis to combine three genome-wide scans totaling 8,816 individuals …
imputation and meta-analysis to combine three genome-wide scans totaling 8,816 individuals …
Single-cell transcriptomics of pancreatic cancer precursors demonstrates epithelial and microenvironmental heterogeneity as an early event in neoplastic progression
Purpose: Early detection of pancreatic ductal adenocarcinoma (PDAC) remains elusive.
Precursor lesions of PDAC, specifically intraductal papillary mucinous neoplasms (IPMNs), …
Precursor lesions of PDAC, specifically intraductal papillary mucinous neoplasms (IPMNs), …
A genome‐wide approach to children's aggressive behavior: The EAGLE consortium
…, F Rivadeneira, A Rodriguez, PA Scheet… - American Journal of …, 2016 - Wiley Online Library
Individual differences in aggressive behavior emerge in early childhood and predict
persisting behavioral problems and disorders. Studies of antisocial and severe aggression in …
persisting behavioral problems and disorders. Studies of antisocial and severe aggression in …
Attention-deficit/hyperactivity disorder polygenic risk scores predict attention problems in a population-based sample of children
Objective Clinically, attention-deficit/hyperactivity disorder (ADHD) is characterized by
hyperactivity, impulsivity, and inattention and is among the most common childhood disorders. …
hyperactivity, impulsivity, and inattention and is among the most common childhood disorders. …
A genome-wide association meta-analysis of preschool internalizing problems
Objective Preschool internalizing problems (INT) are highly heritable and moderately genetically
stable from childhood into adulthood. Gene-finding studies are scarce. In this study, the …
stable from childhood into adulthood. Gene-finding studies are scarce. In this study, the …
Defining the comprehensive genomic landscapes of pancreatic ductal adenocarcinoma using real-world endoscopic aspiration samples
Purpose: Most patients with pancreatic ductal adenocarcinoma (PDAC) present with surgically
unresectable cancer. As a result, endoscopic ultrasound–guided fine-needle aspiration (…
unresectable cancer. As a result, endoscopic ultrasound–guided fine-needle aspiration (…
Augmented lipocalin-2 is associated with chronic obstructive pulmonary disease and counteracts lung adenocarcinoma development
…, II Wistuba, SJ Moghaddam, PA Scheet… - American journal of …, 2021 - atsjournals.org
Rationale: Early pathogenesis of lung adenocarcinoma (LUAD) remains largely unknown.
We found that, relative to wild-type littermates, the innate immunomodulator Lcn2 (lipocalin-2) …
We found that, relative to wild-type littermates, the innate immunomodulator Lcn2 (lipocalin-2) …
Interstitial lung abnormalities after hospitalization for COVID‐19 in patients with cancer: A prospective cohort study
Introduction Survivors of SARS‐CoV‐2 pneumonia often develop persistent respiratory symptom
and interstitial lung abnormalities (ILAs) after infection. Risk factors for ILA development …
and interstitial lung abnormalities (ILAs) after infection. Risk factors for ILA development …
Mutational Heterogeneity in APC and KRAS Arises at the Crypt Level and Leads to Polyclonality in Early Colorectal Tumorigenesis
Purpose: The majority of genomic alterations causing intratumoral heterogeneity (ITH) in
colorectal cancer are thought to arise during early stages of carcinogenesis as a burst but only …
colorectal cancer are thought to arise during early stages of carcinogenesis as a burst but only …
A prospective study of the effects of breastfeeding and FADS2 polymorphisms on cognition and hyperactivity/attention problems
Breastfeeding has been associated with improved cognitive functioning. There is a beneficial
effect on IQ, and possibly on associated phenotypes such as attention problems. It has …
effect on IQ, and possibly on associated phenotypes such as attention problems. It has …