User profiles for Paul C. Evans

Paul C Evans

Imperial college London or university of Sheffield or babraham or Queen Mary University of …
Verified email at sheffield.ac.uk
Cited by 13284

Piezo1 integration of vascular architecture with physiological force

…, RM Cubbon, MT Kearney, KR Prasad, PC Evans… - Nature, 2014 - nature.com
The mechanisms by which physical forces regulate endothelial cells to determine the
complexities of vascular structure and function are enigmatic 1 , 2 , 3 , 4 , 5 . Studies of sensory …

Endothelial dysfunction in COVID-19: a position paper of the ESC Working Group for Atherosclerosis and Vascular Biology, and the ESC Council of Basic …

PC Evans, GE Rainger, JC Mason… - Cardiovascular …, 2020 - academic.oup.com
The COVID-19 pandemic is an unprecedented healthcare emergency causing mortality and
illness across the world. Although primarily affecting the lungs, the SARS-CoV-2 virus also …

Microchimerism and HLA-compatible relationships of pregnancy in scleroderma

…, T Gooley, PC Evans, A Smith, MA Bean, C Ober… - The Lancet, 1998 - thelancet.com
Background Fetal cells can be found in the maternal circulation in most pregnancies. Fetal
progenitor cells have been found to persist in the circulation of women many years after …

Biomechanical factors in atherosclerosis: mechanisms and clinical implications

…, C Weber, JJ Wentzel, PC Evans - European heart …, 2014 - academic.oup.com
Blood vessels are exposed to multiple mechanical forces that are exerted on the vessel wall
(radial, circumferential and longitudinal forces) or on the endothelial surface (shear stress). …

[HTML][HTML] Microchimerism of maternal origin persists into adult life

…, D Myerson, K Rupert, PC Evans… - The Journal of …, 1999 - Am Soc Clin Investig
Recent studies indicate that fetal cells persist in maternal blood for decades after pregnancy.
Maternal cells are known to engraft and persist in infants with immunodeficiency, but …

Long-term fetal microchimerism in peripheral blood mononuclear cell subsets in healthy women and women with scleroderma

PC Evans, N Lambert, S Maloney… - Blood, The Journal …, 1999 - ashpublications.org
Fetal CD34 + CD38 + cells have recently been found to persist in maternal peripheral blood
for many years after pregnancy. CD34 + CD38 + cells are progenitor cells that can …

Endothelial responses to shear stress in atherosclerosis: a novel role for developmental genes

…, TJ Chico, V Ridger, H Roddie, PC Evans - Nature Reviews …, 2020 - nature.com
Flowing blood generates a frictional force called shear stress that has major effects on vascular
function. Branches and bends of arteries are exposed to complex blood flow patterns that …

Activation of Nrf2 in endothelial cells protects arteries from exhibiting a proinflammatory state

…, DO Haskard, JC Mason, PC Evans - … , and vascular biology, 2009 - Am Heart Assoc
Objective— Proinflammatory mediators influence atherosclerosis by inducing adhesion
molecules (eg, VCAM-1) on endothelial cells (ECs) via signaling intermediaries including p38 …

Role of nuclear factor κB in cardiovascular health and disease

…, S Cuhlmann, LA Luong, M Zakkar, PC Evans - Clinical …, 2010 - portlandpress.com
Cardiovascular pathologies are still the primary cause of death worldwide. The molecular
mechanisms behind these pathologies have not been fully elucidated. Unravelling them will …

Endothelial–mesenchymal transition in atherosclerosis

C Souilhol, MC Harmsen, PC Evans… - Cardiovascular …, 2018 - academic.oup.com
Atherosclerosis is an inflammatory disease resulting in the hardening and thickening of the
wall of arteries and the formation of plaques, which comprise immune cells, mesenchymal …