User profiles for Paul C. Evans
Paul C EvansImperial college London or university of Sheffield or babraham or Queen Mary University of … Verified email at sheffield.ac.uk Cited by 13284 |
Piezo1 integration of vascular architecture with physiological force
The mechanisms by which physical forces regulate endothelial cells to determine the
complexities of vascular structure and function are enigmatic 1 , 2 , 3 , 4 , 5 . Studies of sensory …
complexities of vascular structure and function are enigmatic 1 , 2 , 3 , 4 , 5 . Studies of sensory …
Endothelial dysfunction in COVID-19: a position paper of the ESC Working Group for Atherosclerosis and Vascular Biology, and the ESC Council of Basic …
The COVID-19 pandemic is an unprecedented healthcare emergency causing mortality and
illness across the world. Although primarily affecting the lungs, the SARS-CoV-2 virus also …
illness across the world. Although primarily affecting the lungs, the SARS-CoV-2 virus also …
Microchimerism and HLA-compatible relationships of pregnancy in scleroderma
Background Fetal cells can be found in the maternal circulation in most pregnancies. Fetal
progenitor cells have been found to persist in the circulation of women many years after …
progenitor cells have been found to persist in the circulation of women many years after …
Biomechanical factors in atherosclerosis: mechanisms and clinical implications
Blood vessels are exposed to multiple mechanical forces that are exerted on the vessel wall
(radial, circumferential and longitudinal forces) or on the endothelial surface (shear stress). …
(radial, circumferential and longitudinal forces) or on the endothelial surface (shear stress). …
[HTML][HTML] Microchimerism of maternal origin persists into adult life
…, D Myerson, K Rupert, PC Evans… - The Journal of …, 1999 - Am Soc Clin Investig
Recent studies indicate that fetal cells persist in maternal blood for decades after pregnancy.
Maternal cells are known to engraft and persist in infants with immunodeficiency, but …
Maternal cells are known to engraft and persist in infants with immunodeficiency, but …
Long-term fetal microchimerism in peripheral blood mononuclear cell subsets in healthy women and women with scleroderma
Fetal CD34 + CD38 + cells have recently been found to persist in maternal peripheral blood
for many years after pregnancy. CD34 + CD38 + cells are progenitor cells that can …
for many years after pregnancy. CD34 + CD38 + cells are progenitor cells that can …
Endothelial responses to shear stress in atherosclerosis: a novel role for developmental genes
Flowing blood generates a frictional force called shear stress that has major effects on vascular
function. Branches and bends of arteries are exposed to complex blood flow patterns that …
function. Branches and bends of arteries are exposed to complex blood flow patterns that …
Activation of Nrf2 in endothelial cells protects arteries from exhibiting a proinflammatory state
Objective— Proinflammatory mediators influence atherosclerosis by inducing adhesion
molecules (eg, VCAM-1) on endothelial cells (ECs) via signaling intermediaries including p38 …
molecules (eg, VCAM-1) on endothelial cells (ECs) via signaling intermediaries including p38 …
Role of nuclear factor κB in cardiovascular health and disease
Cardiovascular pathologies are still the primary cause of death worldwide. The molecular
mechanisms behind these pathologies have not been fully elucidated. Unravelling them will …
mechanisms behind these pathologies have not been fully elucidated. Unravelling them will …
Endothelial–mesenchymal transition in atherosclerosis
C Souilhol, MC Harmsen, PC Evans… - Cardiovascular …, 2018 - academic.oup.com
Atherosclerosis is an inflammatory disease resulting in the hardening and thickening of the
wall of arteries and the formation of plaques, which comprise immune cells, mesenchymal …
wall of arteries and the formation of plaques, which comprise immune cells, mesenchymal …