Hypoxia drives transient site-specific copy gain and drug-resistant gene expression

…, C Van Rechem, B Ladd, P d Burrowes… - Genes & …, 2015 - genesdev.cshlp.org
Copy number heterogeneity is a prominent feature within tumors. The molecular basis for
this heterogeneity remains poorly characterized. Here, we demonstrate that hypoxia induces …

Protein polyglutamylation catalyzed by the bacterial calmodulin-dependent pseudokinase SidJ

A Sulpizio, ME Minelli, M Wan, PD Burrowes, X Wu… - Elife, 2019 - elifesciences.org
10.7554/eLife.51162.001 Pseudokinases are considered to be the inactive counterparts of
conventional protein kinases and comprise approximately 10% of the human and mouse …

A Coding Single-Nucleotide Polymorphism in Lysine Demethylase KDM4A Associates with Increased Sensitivity to mTOR Inhibitors

…, P Greninger, Y Zhao, C Donado, P Burrowes… - Cancer discovery, 2015 - AACR
SNPs occur within chromatin-modulating factors; however, little is known about how these
variants within the coding sequence affect cancer progression or treatment. Therefore, there is …

Abstract NTOC-110: UNEXPECTED ROLES FOR KDM4A: PROTEIN SYNTHESIS AND MTOR INHIBITOR SENSITIVITY

…, M Boukhali, C Donado, MJ Aryee, P Burrowes… - Clinical Cancer …, 2017 - AACR
Single nucleotide polymorphisms (SNPs) occur within chromatin-modulating factors;
however, little is known about how these variants within the coding sequence impact cancer …

[PDF][PDF] In Vitro Ubiquitination of an Arrestin-related Trafficking Adaptor by the Schizosaccharomyces Pombe E3 Ligase Pub1

PD Burrowes - 2019 - ecommons.cornell.edu
… BIOGRAPHICAL SKETCH Paul Burrowes began his science education early in high
school thanks to a week-long crashcourse in genetics and molecular biology taught by Dr. …

Contrast-enhanced US approach to the diagnosis of focal liver masses

DP Burrowes, A Medellin, AC Harris, L Milot… - Radiographics, 2017 - pubs.rsna.org
… (d) CEUS image obtained at 3 minutes shows weak and late washout. Many bubbles remain
in the lesion on d. (… (d) CEUS image obtained at 3 minutes shows weak and late washout. …

[HTML][HTML] Probability of cancer in pulmonary nodules detected on first screening CT

…, K Amjadi, A Tremblay, P Burrowes… - New England journal …, 2013 - Mass Medical Soc
Background Major issues in the implementation of screening for lung cancer by means of
low-dose computed tomography (CT) are the definition of a positive result and the …

[BOOK][B] The Yemen Arab Republic: The Politics of Development, 1962-1986

RD Burrowes - 2016 - taylorfrancis.com
Examining political and socioeconomic change in the Yemen Arab Republic (YAR), this book,
first published in 1987, focuses primarily on the quarter century following the overthrow of …

Focal pulmonary abnormalities: evaluation with F-18 fluorodeoxyglucose PET scanning.

…, VJ Lowe, JM Hoffman, SS Paine, P Burrowes… - Radiology, 1993 - pubs.rsna.org
The authors assessed the role of positron emission tomography (PET) with fluorine-18
fluorodeoxyglucose (FDG) in differentiation of benign from malignant focal pulmonary …

From letter to spirit:: The transformation of Torah in Paul's symbolic world as reflected in his letter to the Romans

BD Burrowes - 2004 - etheses.dur.ac.uk
… In this thesis the transformation of Paul's thought regarding Torah is analyzed. A
combination of theological and sociological approaches are used in the attempt to discern what …