Genomic evidence for reinfection with SARS-CoV-2: a case study
RL Tillett, JR Sevinsky, PD Hartley… - The Lancet infectious …, 2021 - thelancet.com
Background The degree of protective immunity conferred by infection with severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently unknown. As such, the possibility …
respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently unknown. As such, the possibility …
[HTML][HTML] Histone variant H2A. Z marks the 5′ ends of both active and inactive genes in euchromatin
RM Raisner, PD Hartley, MD Meneghini, MZ Bao… - Cell, 2005 - cell.com
In S. cerevisiae, histone variant H2A.Z is deposited in euchromatin at the flanks of silent
heterochromatin to prevent its ectopic spread. We show that H2A.Z nucleosomes are found at …
heterochromatin to prevent its ectopic spread. We show that H2A.Z nucleosomes are found at …
Chromosome-scale shotgun assembly using an in vitro method for long-range linkage
…, A Fields, PD Hartley, CW Sugnet, D Haussler… - Genome …, 2016 - genome.cshlp.org
Long-range and highly accurate de novo assembly from short-read data is one of the most
pressing challenges in genomics. Recently, it has been shown that read pairs generated by …
pressing challenges in genomics. Recently, it has been shown that read pairs generated by …
[HTML][HTML] Mechanisms that specify promoter nucleosome location and identity
PD Hartley, HD Madhani - Cell, 2009 - cell.com
The chromatin architecture of eukaryotic gene promoters is generally characterized by a
nucleosome-free region (NFR) flanked by at least one H2A.Z variant nucleosome. …
nucleosome-free region (NFR) flanked by at least one H2A.Z variant nucleosome. …
[PDF][PDF] CBFβ stabilizes HIV Vif to counteract APOBEC3 at the expense of RUNX1 target gene expression
DY Kim, E Kwon, PD Hartley, DC Crosby, S Mann… - Molecular cell, 2013 - cell.com
The HIV-1 accessory protein Vif hijacks a cellular Cullin-RING ubiquitin ligase, CRL5, to
promote degradation of the APOBEC3 (A3) family of restriction factors. Recently, the cellular …
promote degradation of the APOBEC3 (A3) family of restriction factors. Recently, the cellular …
Combinatorial, site-specific requirement for heterochromatic silencing factors in the elimination of nucleosome-free regions
JF Garcia, PA Dumesic, PD Hartley… - Genes & …, 2010 - genesdev.cshlp.org
High-resolution nucleosome occupancy maps of heterochromatic regions of wild-type and
silencing-defective mutants of the fission yeast Schizosaccharomyces pombe revealed that …
silencing-defective mutants of the fission yeast Schizosaccharomyces pombe revealed that …
[HTML][HTML] Genomic surveillance of Nevada patients revealed prevalence of unique SARS-CoV-2 variants bearing mutations in the RdRp gene
Patients with signs of COVID-19 were tested through diagnostic RT-PCR for SARS-CoV-2
using RNA extracted from the nasopharyngeal/nasal swabs. To determine the variants of …
using RNA extracted from the nasopharyngeal/nasal swabs. To determine the variants of …
[HTML][HTML] Detecting SARS-CoV-2 variants in wastewater and their correlation with circulating variants in the communities
Detection of SARS-CoV-2 viral load in wastewater has been highly informative in estimating
the approximate number of infected individuals in the surrounding communities. Recent …
the approximate number of infected individuals in the surrounding communities. Recent …
[HTML][HTML] Significance of wastewater surveillance in detecting the prevalence of SARS-CoV-2 variants and other respiratory viruses in the community–A multi-site …
Detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral genome
in wastewater has proven to be useful for tracking the trends of virus prevalence within the …
in wastewater has proven to be useful for tracking the trends of virus prevalence within the …
Developmental Genetics of Secretory Vesicle Acidification During Caenorhabditis elegans Spermatogenesis
EJ Gleason, PD Hartley, M Henderson, KL Hill-Harfe… - Genetics, 2012 - academic.oup.com
Secretory vesicles are used during spermatogenesis to deliver proteins to the cell surface.
In Caenorhabditis elegans, secretory membranous organelles (MO) fuse with the plasma …
In Caenorhabditis elegans, secretory membranous organelles (MO) fuse with the plasma …