Negative carbon isotope anomalies in carbonate rocks bracketing Neoproterozoic glacial
deposits in Namibia, combined with estimates of thermal subsidence history, suggest that …

Comparative geology suggests that the continents adjacent to northern, western, southern,
and eastern Laurentia in the Late Proterozoic were Siberia, Australia-Antarctica, southern …

The gradual discovery that late Neoproterozoic ice sheets extended to sea level near the
equator poses a palaeoenvironmental conundrum. Was the Earth's orbital obliquity > 60 (…

Cratons are large areas of continental lithosphere that have remained coherent and relatively
rigid since the Precambrian. Laurentia, the North American craton, is one of the oldest and …

It is postulated that a mantle superswell (convective upwelling thousands of kilometres in
diameter) developed beneath a stationary supercontinent aggregated in the late Early …

The simultaneous measurement of multiple modalities represents an exciting frontier for
single-cell genomics and necessitates computational methods that can define cellular states …

Computational single-cell RNA-seq (scRNA-seq) methods have been successfully applied to
experiments representing a single condition, technology, or species to discover and define …

Single-cell transcriptomics has transformed our ability to characterize cell states, but deep
biological understanding requires more than a taxonomic listing of clusters. As new methods …

Oligodendroglia support axon survival and function through mechanisms independent of
myelination, and their dysfunction leads to axon degeneration in several diseases. The cause …

North America is an old continent. Whereas South America and Africa were not assembled
until 0.7 Ga, and the assembly of Eurasia began at 0.3 Ga, most of the North American craton …