User profiles for Paul Hofman

Paul L Hofman

Liggins Institute, University of Auckland
Verified email at auckland.ac.nz
Cited by 14796

Fetal origins of hyperphagia, obesity, and hypertension and postnatal amplification by hypercaloric nutrition

…, BH Breier, WS Cutfield, PL Hofman… - American Journal …, 2000 - journals.physiology.org
Environmental factors and diet are generally believed to be accelerators of obesity and
hypertension, but they are not the underlying cause. Our animal model of obesity and …

Migraine as a risk factor for subclinical brain lesions

MC Kruit, MA van Buchem, PAM Hofman, JTN Bakkers… - Jama, 2004 - jamanetwork.com
ContextClinical series have suggested an increased prevalence of cerebral infarction and
white matter lesions (WMLs) in migraine patients. It is not known whether these lesions are …

[HTML][HTML] Premature birth and later insulin resistance

PL Hofman, F Regan, WE Jackson… - … England Journal of …, 2004 - Mass Medical Soc
Background Term infants who are small for gestational age appear prone to the development
of insulin resistance during childhood. We hypothesized that insulin resistance, a marker of …

Cerebral hyperperfusion syndrome

…, WH Mess, PAM Hofman… - The Lancet …, 2005 - thelancet.com
Cerebral hyperperfusion syndrome (CHS) after carotid endarterectomy is characterised by
ipsilateral headache, hypertension, seizures, and focal neurological deficits. If not treated …

Relearning sound localization with new ears

PM Hofman, JGA Van Riswick, AJ Van Opstal - Nature neuroscience, 1998 - nature.com
Because the inner ear is not organized spatially, sound localization relies on the neural
processing of implicit acoustic cues. To determine a sound's position, the brain must learn and …

A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease

…, B Mograbi, A Darfeuille-Michaud, P Hofman - Nature …, 2011 - nature.com
Susceptibility to Crohn's disease, a complex inflammatory disease, is influenced by common
variants at many loci. The common exonic synonymous SNP (c.313C>T) in IRGM, found in …

Insulin resistance in short children with intrauterine growth retardation

PL Hofman, WS Cutfield, EM Robinson… - The Journal of …, 1997 - academic.oup.com
Epidemiological studies have demonstrated an association between intrauterine growth
retardation and an increased risk of adult diseases that include essential hypertension, …

Blood-brain barrier leakage in patients with early Alzheimer disease

…, MA Van Buchem, M Muller, PAM Hofman… - Radiology, 2016 - pubs.rsna.org
Purpose To investigate whether the blood-brain barrier (BBB) leaks blood-circulating substances
in patients with early forms of Alzheimer disease (AD), and if so, to examine the extent …

[HTML][HTML] Pulmonary pathology and COVID-19: lessons from autopsy. The experience of European Pulmonary Pathologists

F Calabrese, F Pezzuto, F Fortarezza, P Hofman, I Kern… - Virchows archiv, 2020 - Springer
Since its initial recognition in December 2019, Coronavirus disease 19 (COVID-19) has quickly
spread to a pandemic infectious disease. The causative agent has been recognized as a …

External validation of the Canadian CT Head Rule and the New Orleans Criteria for CT scanning in patients with minor head injury

…, PE Vos, DR Kool, PJ Nederkoorn, PAM Hofman… - Jama, 2005 - jamanetwork.com
ContextTwo decision rules for indications of computed tomography (CT) in patients with
minor head injury, the Canadian CT Head Rule (CCHR) and the New Orleans Criteria (NOC), …