User profiles for Paul M. Airs

Paul M Airs

Post doctoral researcher, JCBC Wellcome trust MRC Cambridge stem cell institute
Verified email at cam.ac.uk
Cited by 297

[HTML][HTML] RNA interference for mosquito and mosquito-borne disease control

PM Airs, LC Bartholomay - Insects, 2017 - mdpi.com
RNA interference (RNAi) is a powerful tool to silence endogenous mosquito and mosquito-borne
pathogen genes in vivo. As the number of studies utilizing RNAi in basic research …

Understanding the role of wild ruminants in anthelmintic resistance in livestock

TL Brown, PM Airs, S Porter, P Caplat… - Biology …, 2022 - royalsocietypublishing.org
Wild ruminants are susceptible to infection from generalist helminth species, which can also
infect domestic ruminants. A better understanding is required of the conditions under which …

Arthropod viruses and small RNAs

D Vijayendran, PM Airs, K Dolezal… - Journal of Invertebrate …, 2013 - Elsevier
The recently characterized small RNAs provide a new paradigm for physiological studies.
These molecules have been shown to be integral players in processes as diverse as …

[HTML][HTML] Genetic and functional diversification of chemosensory pathway receptors in mosquito-borne filarial nematodes

…, PM Airs, A Mann, LC Bartholomay, M Zamanian - PLoS …, 2020 - journals.plos.org
Lymphatic filariasis (LF) afflicts over 60 million people worldwide and leads to severe
pathological outcomes in chronic cases. The nematode parasites (Nematoda: Filarioidea) that …

[HTML][HTML] Low-cost molecular methods to characterise gastrointestinal nematode co-infections of goats in Africa

PM Airs, J Ventura-Cordero, W Mvula, T Takahashi… - Parasites & …, 2023 - Springer
Background Veterinary diagnostics aid intervention strategies, track zoonoses, and direct
selective breeding programs in livestock. In ruminants, gastrointestinal nematode (GIN) …

Resolving the origins of secretory products and anthelmintic responses in a human parasitic nematode at single-cell resolution

CR Henthorn, PM Airs, EK Neumann, M Zamanian - Elife, 2023 - elifesciences.org
Nematode excretory-secretory (ES) products are essential for the establishment and maintenance
of infections in mammals and are valued as therapeutic and diagnostic targets. While …

[HTML][HTML] A comparative analysis of RNAi trigger uptake and distribution in mosquito vectors of disease

PM Airs, KE Kudrna, B Lubinski, Y Phanse… - Insects, 2023 - mdpi.com
Simple Summary RNA interference (RNAi) is a widely conserved antiviral mechanism
whereby double-stranded RNA (dsRNA) is identified and degraded in cells through the RNAi …

[HTML][HTML] Biodistribution and toxicity studies of PRINT hydrogel nanoparticles in mosquito larvae and cells

Y Phanse, BM Dunphy, JL Perry, PM Airs… - PLoS neglected …, 2015 - journals.plos.org
Mosquito-borne diseases continue to remain major threats to human and animal health and
impediments to socioeconomic development. Increasing mosquito resistance to chemical …

[HTML][HTML] Spatial transcriptomics reveals antiparasitic targets associated with essential behaviors in the human parasite Brugia malayi

PM Airs, K Vaccaro, KJ Gallo, N Dinguirard… - PLoS …, 2022 - journals.plos.org
Lymphatic filariasis (LF) is a chronic debilitating neglected tropical disease (NTD) caused by
mosquito-transmitted nematodes that afflicts over 60 million people. Control of LF relies on …

Impact of sugar composition on meal distribution, longevity, and insecticide toxicity in Aedes aegypti

PM Airs, KE Kudrna, LC Bartholomay - Acta tropica, 2019 - Elsevier
Toxic Sugar Baits (TSBs) are an inexpensive and field-applicable approach to deliver a
variety of insecticides to sugar-seeking mosquitoes. We reasoned that carbohydrate chemistry …