IgA dominates the early neutralizing antibody response to SARS-CoV-2
…, A Mohr, F Anna, L Claër, P Quentric… - Science translational …, 2021 - science.org
Humoral immune responses are typically characterized by primary IgM antibody responses
followed by secondary antibody responses associated with immune memory and composed …
followed by secondary antibody responses associated with immune memory and composed …
Lower disease activity but higher risk of severe COVID-19 and herpes zoster in patients with systemic lupus erythematosus with pre-existing autoantibodies …
…, P Bastard, C Charre, R Lhote, P Quentric… - Annals of the …, 2022 - ard.bmj.com
Objectives Type-I interferons (IFNs-I) have potent antiviral effects. IFNs-I are also overproduced
in patients with systemic lupus erythematosus (SLE). Autoantibodies (AAbs) neutralising …
in patients with systemic lupus erythematosus (SLE). Autoantibodies (AAbs) neutralising …
Distinct cytokine profiles associated with COVID-19 severity and mortality
K Dorgham, P Quentric, M Gökkaya, S Marot… - Journal of Allergy and …, 2021 - Elsevier
Background Markedly elevated levels of proinflammatory cytokines and defective type-I
interferon responses were reported in patients with coronavirus disease 2019 (COVID-19). …
interferon responses were reported in patients with coronavirus disease 2019 (COVID-19). …
[HTML][HTML] Longitudinal cytokine profiling in patients with severe COVID-19 on extracorporeal membrane oxygenation and hemoadsorption
G Lebreton, K Dorgham, P Quentric… - American Journal of …, 2021 - atsjournals.org
Early in the coronavirus disease (COVID-19) pandemic, the description of a cytokine storm
associated with the most severe forms of the disease elicited consideration of anticytokine …
associated with the most severe forms of the disease elicited consideration of anticytokine …
[HTML][HTML] CD8+ PD-L1+ CXCR3+ polyfunctional T cell abundances are associated with survival in critical SARS-CoV-2–infected patients
L Adam, P Rosenbaum, P Quentric, C Parizot… - JCI insight, 2021 - ncbi.nlm.nih.gov
The importance of the adaptive T cell response in the control and resolution of viral infection
has been well established. However, the nature of T cell–mediated viral control …
has been well established. However, the nature of T cell–mediated viral control …
[HTML][HTML] Elevated neopterin levels predict fatal outcome in SARS-CoV-2-infected patients
M Chauvin, M Larsen, B Quirant, P Quentric… - Frontiers in cellular …, 2021 - frontiersin.org
Highlights Innate immune activation during Covid-19 infection is associated with pernicious
clinical outcome. Background Coronavirus disease 2019 (Covid-19) is a worldwide threat …
clinical outcome. Background Coronavirus disease 2019 (Covid-19) is a worldwide threat …
[HTML][HTML] LOX-1-expressing immature neutrophils identify critically-ill COVID-19 patients at risk of thrombotic complications
B Combadiere, L Adam, N Guillou, P Quentric… - Frontiers in …, 2021 - frontiersin.org
Background Lymphopenia and the neutrophil/lymphocyte ratio may have prognostic value
in COVID-19 severity. Objective We investigated neutrophil subsets and functions in blood …
in COVID-19 severity. Objective We investigated neutrophil subsets and functions in blood …
[HTML][HTML] Pre-COVID-19 immunity to common cold human coronaviruses induces a recall-type IgG response to SARS-CoV-2 antigens without cross-neutralisation
…, F Anna, S Marot, A Mathian, M Atif, P Quentric… - Frontiers in …, 2022 - frontiersin.org
The capacity of pre-existing immunity to human common coronaviruses (HCoV) to cross-protect
against de novo COVID-19is yet unknown. In this work, we studied the sera of 175 …
against de novo COVID-19is yet unknown. In this work, we studied the sera of 175 …
[HTML][HTML] Diagnostic yield, safety and therapeutic consequences of myocardial biopsy in clinically suspected fulminant myocarditis unweanable from mechanical …
…, L Lefevre, O Saura, D Levy, P Quentric… - Annals of Intensive …, 2023 - Springer
Background Fulminant myocarditis is a rare and severe disease whose definite and etiological
diagnoses rely on pathological examination. Albeit, myocardial biopsy can be associated …
diagnoses rely on pathological examination. Albeit, myocardial biopsy can be associated …
Phenotypic heterogeneity of fulminant COVID-19--related myocarditis in adults
…, K Dorgham, M Kerneis, S Burrel, P Quentric… - Journal of the American …, 2022 - jacc.org
Background Adults who have been infected with SARS-CoV-2 can develop a multisystem
inflammatory syndrome (MIS-A), including fulminant myocarditis. Yet, several patients fail to …
inflammatory syndrome (MIS-A), including fulminant myocarditis. Yet, several patients fail to …