User profiles for Paul Savelkoul

Paul Savelkoul

Verified email at mumc.nl
Cited by 20265

[HTML][HTML] Dissemination of antimicrobial resistance in microbial ecosystems through horizontal gene transfer

…, S Majumder, LB Van Alphen, PHM Savelkoul… - Frontiers in …, 2016 - frontiersin.org
The emergence and spread of antibiotic resistance among pathogenic bacteria has been a
rising problem for public health in recent decades. It is becoming increasingly recognized …

[HTML][HTML] Extended-spectrum β-lactamase genes of Escherichia coli in chicken meat and humans, The Netherlands

…, L Xu, P Hawkey, M Heck, P Savelkoul… - Emerging infectious …, 2011 - ncbi.nlm.nih.gov
We determined the prevalence and characteristics of extended-spectrum β-lactamase (ESBL)
genes of Enterobacteriaceae in retail chicken meat and humans in the Netherlands. Raw …

New developments in the diagnosis of bloodstream infections

…, SA Danner, PHM Savelkoul… - The Lancet infectious …, 2004 - thelancet.com
New techniques have emerged for the detection of bacteria in blood, because the blood
culture as gold standard is slow and insufficiently sensitive when the patient has previously …

Quantification of bacteria adherent to gastrointestinal mucosa by real-time PCR

…, PHM Savelkoul - Journal of clinical …, 2002 - Am Soc Microbiol
The use of real-time quantitative PCR (5′ nuclease PCR assay) as a tool to study the
gastrointestinal microflora that adheres to the colonic mucosa was evaluated. We developed …

Identification of Epidemic Strains ofAcinetobacter baumannii by Integrase Gene PCR

…, PHM Savelkoul - Journal of clinical …, 2001 - Am Soc Microbiol
Forty-eight clinical Acinetobacter isolates with different epidemic behavior were investigated
for the presence of integrons and plasmids and for antibiotic susceptibility. Integrons were …

Comparison of Seven Techniques for Typing International Epidemic Strains of Clostridium difficile: Restriction Endonuclease Analysis, Pulsed-Field Gel …

…, E Kuijper, J Pepin, EH Frost, P Savelkoul… - Journal of clinical …, 2008 - Am Soc Microbiol
Using 42 isolates contributed by laboratories in Canada, The Netherlands, the United Kingdom,
and the United States, we compared the results of analyses done with seven Clostridium …

Extended-Spectrum β-Lactamase–Producing Escherichia coli From Retail Chicken Meat and Humans: Comparison of Strains, Plasmids, Resistance Genes, and …

…, PHM Savelkoul… - Clinical infectious …, 2013 - academic.oup.com
Background. The worldwide prevalence of extended-spectrum β-lactamase (ESBL)–producing
Enterobacteriaceae is increasing rapidly both in hospitals and in the community. A …

[HTML][HTML] The human microbiome as a reservoir of antimicrobial resistance

J Penders, EE Stobberingh, PHM Savelkoul… - Frontiers in …, 2013 - frontiersin.org
The gut microbiota is amongst the most densely populated microbial ecosystem on earth.
While the microbiome exerts numerous health beneficial functions, the high density of micro-…

Comparison of Real-Time PCR and Culture for Detection of Porphyromonas gingivalis in Subgingival Plaque Samples

…, PHM Savelkoul - Journal of clinical …, 2003 - Am Soc Microbiol
Porphyromonas gingivalis is a major pathogen in destructive periodontal disease in humans.
Detection and quantification of this microorganism are relevant for diagnosis and treatment …

[HTML][HTML] The role of putative phosphorylation sites in the targeting and shuttling of the aquaporin-2 water channel

BWM van Balkom, PJM Savelkoul, D Markovich… - Journal of Biological …, 2002 - ASBMB
In renal collecting ducts, a vasopressin-induced cAMP increase results in the phosphorylation
of aquaporin-2 (AQP2) water channels at Ser-256 and its redistribution from intracellular …