Cytoscape is an open source software project for integrating biomolecular interaction
networks with high-throughput expression data and other molecular states into a unified …

We demonstrate the first successful application of exome sequencing to discover the gene
for a rare mendelian disorder of unknown cause, Miller syndrome (MIM%263750). For four …

Bioconductor is an open-source, open-development software project for the analysis and
comprehension of high-throughput data in genomics and molecular biology. The project aims …

THE control of molecular alignment in liquid-crystal phases at macroscopic scales has been
investigated extensively because of its importance in optical or optoelectronic applications, …

We analyzed the whole-genome sequences of a family of four, consisting of two siblings
and their parents. Family-based sequencing allowed us to delineate recombination sites …

We present a method (the Inferelator) for deriving genome-wide transcriptional regulatory
interactions, and apply the method to predict a large portion of the regulatory network of the …

Investigators have long suspected that pathogenic microbes might contribute to the onset
and progression of Alzheimer's disease (AD) although definitive evidence has not been …

VariantAnnotation is an R / Bioconductor package for the exploration and annotation of genetic
variants. Capabilities exist for reading, writing and filtering variant call format (VCF) files. …

We report the complete sequence of the 4,274,642-bp genome of Haloarcula marismortui, a
halophilic archaeal isolate from the Dead Sea. The genome is organized into nine circular …

The environment significantly influences the dynamic expression and assembly of all
components encoded in the genome of an organism into functional biological networks. We have …